Diet Synergy for Muscle Health

(POTATO Trial)

CC
NA
Overseen ByNicholas A Burd (Full Professor), PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Illinois at Urbana-Champaign
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests how different foods affect muscle health after exercise. Researchers examine how well the body uses protein and builds muscle when consuming potatoes and beef, bread and beef, or just beef post-workout. This approach, called "Diet Synergy," focuses on recreationally active young adults who have not experienced significant weight changes in the last six months. Individuals aged 19 to 40 who exercise regularly may find this trial a great fit. As an unphased trial, it offers a unique opportunity to contribute to understanding how diet impacts muscle health.

Do I need to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Previous studies have shown that eating lean red meat, like beef, is safe and beneficial for muscle health. Participants who included beef in their diet did not experience serious side effects. Regular beef consumption supports muscle protein synthesis, the process that builds muscle. This suggests that the beef treatments in this trial should be well-tolerated.

Research indicates that potato protein effectively aids muscle building, especially when combined with exercise. This potato and beef combination has not raised major safety concerns in past studies.

Regarding the bread and beef combination, studies have paired lean red meat with other foods without major issues. Increasing protein through these foods has proven safe and effective for improving muscle health.

Overall, these treatments have been tested in various settings and are generally safe to consume. Participants in this study are likely to tolerate these food combinations well.12345

Why are researchers excited about this trial?

Researchers are excited about the Diet Synergy treatments because they explore how different food combinations can enhance muscle health after exercise. Unlike standard protein supplements, these treatments use everyday foods like potatoes, bread, and lean beef, which are easily accessible and natural. The combinations, such as Potato and Beef or Bread and Beef, are designed to optimize nutrient intake, offering a novel approach to muscle recovery with varied nutritional profiles. This focus on real food combinations opens up potential for simple, diet-based interventions to boost muscle health effectively.

What evidence suggests that this trial's treatments could be effective for muscle health?

This trial will compare different dietary combinations for muscle health. Research has shown that potato protein can significantly aid in building and repairing muscles, both at rest and after exercise. Studies have found that consuming 30 grams of protein from potatoes effectively boosts this muscle-building process. In this trial, one group will receive a combination of potato and beef. Another group will receive a combination of bread and beef, as evidence suggests that meat aids in muscle recovery and growth after workouts. A third group will receive beef alone, which supports muscle building and is an excellent choice post-exercise. Overall, these combinations appear promising for maintaining healthy muscles and aiding recovery after exercise.26789

Are You a Good Fit for This Trial?

This trial is for recreationally active young adults aged 19-40 who are interested in how different food combinations affect muscle protein synthesis after resistance exercise. Specific eligibility criteria details were not provided, so participants should inquire about any additional requirements.

Inclusion Criteria

Recreationally-active
Weight stable for prior 6 months
I am between 19 and 40 years old.
See 1 more

Exclusion Criteria

I am not between the ages of 20 and 35.
Pregnancy
Irregular menstrual cycles (i.e., around 21-day or around 35-day cycle)
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Preliminary Testing

Participants undergo preliminary testing including anthropometrics, resting metabolic rate, and 10-repetition maximum testing

1 day
1 visit (in-person)

Infusion Trials

Participants undergo stable isotope infusion trials with blood and muscle biopsies, followed by resistance exercise and meal ingestion

2 sessions, at least 7 days apart
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the infusion trials

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Diet Synergy

Trial Overview

The study tests the effects of consuming potato and beef, bread and beef, or just beef on muscle building after a single session of resistance exercise. Participants will undergo blood and muscle tests to see how their bodies process protein.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Potato and Beef (PB)Experimental Treatment2 Interventions
Group II: Bread and Beef (BB)Experimental Treatment2 Interventions
Group III: Beef (B)Experimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Illinois at Urbana-Champaign

Lead Sponsor

Trials
203
Recruited
40,600+

Citations

Functional Properties of Meat in Athletes' Performance and ...

Based on the limited research, meat could be an effective post-exercise food that results in favorable muscle protein synthesis and metabolic ...

Greater Protein Intake Emphasizing Lean Beef Does Not ...

Our findings indicated that greater daily protein intake, emphasizing beef, did not influence RT-induced changes in quadriceps muscle strength or muscle volume ...

Does Beef Protein Supplementation Improve Body ...

Protein supplementation might improve body composition and exercise performance. Supplements containing whey protein (WP) have received the most attention, ...

This type of meat supercharges muscle growth after workouts

Scientists discovered that lean pork builds muscle more effectively post-workout than high-fat pork, even with identical protein levels.

Myoprotective Whole Foods, Muscle Health and Sarcopenia

Observational studies involving whole foods and muscle-related outcomes in older adults aged ≥ 50 years. Ref. Beef intake in the past 12 months assessed by the ...

Effect of lean red meat combined with a multicomponent ...

Exercise and increased dietary protein have been linked to improved muscle and cognitive health, but the combination may be more effective.

The Influence of Regular Beef Consumption and Protein ...

To determine if regular beef consumption as part of a higher protein diet aids the muscle adaptive response to resistance training and improvements in cognition ...

The effects of a protein enriched diet with lean red meat ... - PMC

The primary aim of this study is to investigate whether a modest increase in dietary protein achieved through the consumption of lean red meat three days per ...

Protein Supplementation with Low Fat Meat after ...

Beef is a nutrient-rich, high-quality protein containing all the essential amino acids in proportions similar to those found in human skeletal muscle.