Multivitamins for Healthy Aging
(MiMIC Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines how multivitamins might aid healthy aging. Researchers aim to determine if these vitamins can enhance metabolism and energy by analyzing blood cells and other health markers. Participants will be divided into three groups: one taking the "GOLD" blend of vitamins (MVM Gold Blend), another taking the "Core" blend (MVM Core Blend), and a third taking a placebo (a pill with no active ingredients). Individuals who are sedentary, aged 40 to 60, and not currently taking similar supplements might be suitable candidates.
As an unphased trial, this study provides a unique opportunity to contribute to understanding the potential benefits of multivitamins for healthy aging.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that multivitamin and mineral (MVM) supplements are generally safe and well-tolerated. Studies have found that these supplements can increase vitamin C and zinc levels in the blood without harming the immune system, suggesting they are unlikely to cause harmful changes in the body.
However, some reports mention that certain ingredients in MVM supplements might cause side effects. For instance, rare cases have linked some ingredients to an increased risk of lung cancer, though the risk appears low.
Overall, MVM supplements are considered safe for most people, but consulting a healthcare provider before starting any new supplement is advisable.12345Why are researchers excited about this trial's treatments?
Researchers are excited about the MVM Core Blend and MVM Gold Blend multivitamins for healthy aging because they offer a fresh take on traditional multivitamin supplements. Unlike standard multivitamins, the MVM Core Blend is specifically modified to enhance the consumer experience by adjusting the levels of specific nutrients. Meanwhile, the MVM Gold Blend aims to harmonize vitamin and mineral formulations globally, making it versatile for different markets while maintaining essential nutrient levels. These innovative approaches could provide more tailored and effective supplementation options for individuals aiming to support healthier aging.
What evidence suggests that this trial's treatments could be effective for healthy aging?
Research has shown that taking multivitamins and minerals (MVM) can support healthy aging. Studies suggest that MVMs may slow the aging process by about four months over two years and may delay brain aging by up to two years. Many individuals report feeling more youthful and energetic when taking them. In this trial, participants will receive either the MVM Core Blend or the MVM Gold Blend. Research indicates that both blends may improve stress, mild mental health issues, and tiredness. Overall, MVMs are associated with better health and vitality.12367
Who Is on the Research Team?
Anthony Molina, PhD
Principal Investigator
UC San Diego
Are You a Good Fit for This Trial?
This trial is for men and women aged 40-60 who are generally healthy but sedentary. Participants should not have major health issues or be taking other supplements that could affect the results.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Baseline assessments including blood draw, vital signs, and physical assessments
Treatment
Participants receive daily oral tablet of MVM or placebo for 14 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MVM Core Blend
- MVM Gold Blend
Trial Overview
The study tests two different daily multivitamin and mineral blends (MVM Core Blend and MVM Gold Blend) against a placebo to see how they affect markers of healthy aging, like cell function, metabolism, physical ability, and muscle quality. Participants are randomly assigned to one group.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Placebo Group
Because Centrum is a global multivitamin/multimineral brand, it has numerous product formulations for different regions/markets around the world. To better harmonize these formulations across key markets, a 'core' blend of vitamins and minerals has been designed at levels that can be leveraged across different markets - this is internally being referred to as the MVM "GOLD" Blend formula. This will be consumed once per day for the duration of the study.
This is a modification to currently marketed Centrum Adult in which select nutrients have been removed or lowered to provide a better consumer experience. This will be consumed once per day for the duration of the study.
The placebo is a pill of the same color, size, and density as the experimental pills. It contains no vitamins or minerals. It will be administered once a day as the experimental pills.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor
HALEON
Industry Sponsor
Citations
Multivitamin and Mineral Supplementation and Healthy Aging
The goal of this study is to determine the impact of MVM supplementation on clinical and biochemical markers associated with healthy aging, ...
A rapid review of meta-analyses on health outcomes
Overall, RCT findings indicate that MVM supplementation reduces stress, mild psychiatric symptoms, and fatigue in healthy adults, with stronger effects in ...
The role of multivitamin and mineral supplements in ... - PMC
Results. A total of 93% of users agreed that MVM supplements support at least one out of six youthful vitality benefits. Users reported several ...
A new study this week found that taking a daily multivitamin ...
A new study this week found that taking a daily multivitamin significantly reduces the rate of biological aging. But there's a problem.
5.
news.harvard.edu
news.harvard.edu/gazette/story/2026/03/daily-multivitamin-may-slow-biological-aging/Daily multivitamin may slow biological aging
The changes equated to about four months less biological aging over the course of two years. Additionally, people who were biologically older ...
The Impacts of Multivitamin and Mineral Supplementation ...
1.1 SYNOPSIS. Title: The Impacts of Multivitamin and Mineral Supplementation on Cellular Metabolism and Healthy. Aging. Study Description: The goal is to ...
7.
nutraingredients.com
nutraingredients.com/Article/2026/03/25/multivitamin-minerals-linked-to-slower-aging/'Exciting': Multivitamin-minerals linked to slower aging
Two years of daily supplementation with a multivitamin-mineral may slow aging in older adults, says a new data from the COcoa Supplement and ...
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