Remote Exercise for Prostate Cancer
(RE-FIT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether a Remote Supervised Exercise Program can benefit World Trade Center responders with prostate cancer. Many of these men experience fatigue and a reduced quality of life after cancer treatment. The study aims to determine if a video-based exercise routine, performed three times a week, can enhance physical strength and well-being. Men who have undergone prostate cancer treatment, exercise less than 90 minutes a week, and can participate in video workouts might be suitable candidates. The trial will also assess whether participants can collect saliva samples at home for future research. As an unphased trial, this study offers a unique opportunity to contribute to research that could improve the quality of life for others facing similar challenges.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, it mentions that participants may be on active surveillance or receiving androgen deprivation therapy, suggesting that some medications might be allowed.
What prior data suggests that this remote exercise program is safe for prostate cancer patients?
Previous studies have found remote exercise programs for prostate cancer patients to be safe and well-tolerated. Research shows that participants completed most exercise sessions, with men finishing 90% of aerobic sessions and 96% of resistance training sessions. Other studies have found that supervised exercise programs are generally safe and can enhance the quality of life for individuals with prostate cancer.
These studies reported no serious side effects, indicating that participants did not experience major health problems from the exercise. The exercises, including heart-pumping aerobic activities, strength, balance, and flexibility exercises, are designed to be safe for people with varying fitness levels. These findings suggest that joining a remote exercise program could safely improve physical function and well-being for WTC Responders with prostate cancer.12345Why are researchers excited about this trial?
Researchers are excited about the Remote Supervised Exercise Program for prostate cancer because it offers a unique, accessible approach to managing the condition. Unlike traditional in-person exercise programs, this treatment is delivered remotely via live videoconferencing, making it more convenient for participants to join from their homes. The program's individualized approach, which tailors exercise intensity and progression based on each participant's ability, ensures safety and maximizes effectiveness. Additionally, the inclusion of a certified instructor providing real-time supervision and safety monitoring enhances participant confidence and engagement.
What evidence suggests that this remote exercise program is effective for prostate cancer?
Research shows that supervised exercise can greatly improve the quality of life for prostate cancer patients. In this trial, participants in the Remote Exercise Intervention arm will follow a remote exercise program, which studies have shown significantly improves health and reduces symptoms for these patients. Such exercise programs can also help prevent weight gain, lower blood pressure, and improve physical abilities. Feedback from similar trials indicates that participants find remote supervised programs easy to follow and helpful. Overall, these findings suggest that the exercise program could enhance physical function and well-being for participants.23567
Are You a Good Fit for This Trial?
This trial is for World Trade Center responders who have had prostate cancer, finished their initial treatment, and currently do little regular exercise. Participants must be able to walk on their own, use videoconferencing, understand English, and not have serious medical issues or metastatic cancer.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants in the exercise group will attend three one-hour exercise sessions per week using videoconferencing for 16 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment, including remote physical function testing and questionnaires
Waitlist Control
Participants in the waitlist control group receive usual care during the 16-week study period and are offered the exercise program after completing all study assessments
What Are the Treatments Tested in This Trial?
Interventions
- Remote Supervised Exercise Program
Trial Overview
The study tests a live, remote group exercise program delivered by video three times a week for 16 weeks versus usual care (waitlist). It aims to see if the program is practical and helpful in improving physical function and quality of life.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants randomized to this arm will participate in a remotely delivered, supervised group exercise program conducted via live videoconferencing. The intervention consists of three 60-minute exercise sessions per week for 16 weeks. Sessions include aerobic, strength, balance, and flexibility exercises and are led by a certified instructor with real-time supervision and safety monitoring. Exercise intensity and progression are individualized based on participant ability and perceived exertion. Participants complete study assessments at baseline and post-intervention, including remote physical function testing, patient-reported outcome questionnaires, wearable physical activity monitoring, and optional saliva collection.
Participants randomized to the waitlist control arm will receive usual medical care and will not participate in the study exercise program during the 16-week study period. They will complete the same study assessments as the intervention arm at baseline and post-intervention, including remote physical function testing, patient-reported outcome questionnaires, wearable physical activity monitoring, and optional saliva collection. After completion of all post-intervention assessments, participants in the waitlist control arm will be offered the remote exercise program; data collected during this post-study period will not be included in the primary analyses.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Vermont
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Collaborator
Citations
Improving Quality of Life Through Supervised Exercise ... - PMC
Conclusions: Supervised therapeutic exercise is associated with significant improvements in QoL in breast and prostate cancer patients. Combined and well- ...
Home-based versus supervised group exercise in men ...
A HOME exercise intervention appears non-inferior to GROUP for fatigue and functional endurance and requires fewer resources to implement.
Impact of adherence to a remote exercise program on ...
This study demonstrates that adherence to a remote exercise program significantly improves HRQoL and reduces symptom burden in patients with prostate cancer ...
Clinical Research Trial Listing ( Prostate Cancer ...
Comparison of the Effectiveness of Supervised, Video-based and Home-based Resistance Exercise Program in Patients With Prostate Cancer.
Home-based exercise improves quality of life in breast and ...
Conclusions. Home-based exercise results in small improves QoL in BCa/PCa survivors, independent of cancer type, intervention duration and type, or age.
Feasibility, safety, and acceptability of a remotely monitored ...
Men who completed the remote intervention attempted 90% and 96% of prescribed aerobic and resistance training sessions, respectively, and 86% ...
7.
experts.umn.edu
experts.umn.edu/en/publications/feasibility-safety-and-acceptability-of-a-remotely-monitored-exer/A Clinical trial of High-intensity Aerobic and resistance ...
Conclusions: Remotely monitored exercise training is feasible, safe, and acceptable in men with mCRPC; there was no difference in these outcomes by mode of ...
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