1000 Participants NeededMy employer runs this trial

Transcatheter Treatment for Mitral Regurgitation

(CHOICE-MI Trial)

Recruiting at 43 trial locations
WB
SL
LS
Overseen ByLena Strotmann, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Universitätsklinikum Hamburg-Eppendorf
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice.

Patients evaluated for TMVR but not undergoing the procedure are no longer systematically included. Historical data may include such patients who subsequently underwent alternative treatments, including transcatheter edge-to-edge repair, mitral valve surgery, or medical/conservative therapy.

Who Is on the Research Team?

LC

Lenard Conradi, MD

Principal Investigator

University of Cologne

TM

Thomas Modine, MD

Principal Investigator

University Hospital, Bordeaux

JF

Juan F Granada, MD

Principal Investigator

Cardiovascular Research Foundation, New York, USA

SL

Sebastian Ludwig, MD

Principal Investigator

University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf

Are You a Good Fit for This Trial?

Inclusion Criteria

clinically significant mitral insufficiency
patient underwent screening for TMVI
echocardiography data at baseline (and after TMVI, E2E and surgery)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Treatment

Participants undergo transcatheter mitral valve replacement (TMVR) in real-world clinical practice

Follow-up

Participants are monitored for clinical outcomes and mitral insufficiency severity

12 months

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

Universitätsklinikum Hamburg-Eppendorf

Lead Sponsor

Trials
497
Recruited
2,984,000+

Montreal Heart Institute

Collaborator

Trials
125
Recruited
85,400+

University Hospital, Bordeaux

Collaborator

Trials
813
Recruited
825,000+