375 Participants NeededMy employer runs this trial

Mindfulness Meditation + Self-Hypnosis for Chronic Pain

RS
Overseen ByRana Salem, MA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Washington
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how two psychological treatments—mindfulness meditation and therapeutic hypnosis—can help manage chronic pain in older adults. Researchers aim to understand how these treatments affect the brain and determine which individuals benefit most. Participants will be randomly assigned to one of three groups: mindfulness meditation, therapeutic hypnosis, or story listening. This trial suits those aged 60 and older who have experienced chronic pain on most days for at least three months and have not recently practiced meditation or hypnosis. As an unphased trial, it offers a unique opportunity to contribute to innovative research and potentially discover new ways to manage chronic pain.

Will I have to stop taking my current medications?

You don't have to stop taking your current medications, but they must have been stable for at least 4 weeks before the study and should not change during the study.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Past studies have found mindfulness meditation to be generally safe for people with chronic pain. Some reports indicate it might slightly reduce pain, though rare cases of anxiety or distress have occurred. However, most individuals tolerate it well.

Research shows that therapeutic hypnosis is usually safe for people with chronic pain and can significantly reduce pain without major risks. A review found no negative effects when a trained professional performs hypnosis.

For story listening, direct safety data is limited, but it primarily involves listening, which poses low risk. Listening to stories might help people feel understood, offering comfort and safety.

Overall, available research generally considers these treatments safe.12345

Why are researchers excited about this trial?

Researchers are excited about exploring mindfulness meditation, story listening, and therapeutic hypnosis for chronic pain because these approaches offer non-drug alternatives that engage the mind's natural ability to influence pain perception. Unlike standard treatments like NSAIDs, opioids, or physical therapy, these techniques focus on altering the way the brain processes pain signals, potentially reducing reliance on medication and its side effects. Mindfulness meditation helps individuals develop awareness and acceptance of pain, while story listening and therapeutic hypnosis use narrative and suggestive techniques to create a calming mental environment. Together, these methods could offer a holistic and empowering way to manage chronic pain.

What evidence suggests that this trial's treatments could be effective for chronic pain?

Research has shown that mindfulness meditation, one of the treatments in this trial, can reduce pain and improve life quality for people with chronic pain. Studies have found that it leads to small to moderate improvements in pain relief and mental health for those who practice it.

Therapeutic hypnosis, another treatment option in this trial, significantly reduces pain in various chronic pain conditions. Research suggests that hypnosis can lower pain levels and reduce its impact on daily life by about 24%, making it an effective option for pain relief.

Story listening, the third treatment arm in this trial, has not been as extensively studied for pain relief but may help improve confidence in managing pain. Engaging with stories might help people find meaning and cope better with chronic pain.13678

Who Is on the Research Team?

MJ

Mark Jensen, PhD

Principal Investigator

University of Washington

MD

Melissa Day, PhD

Principal Investigator

The University of Queensland

Are You a Good Fit for This Trial?

This trial is for adults aged 60 or older who have had chronic pain (pain most days for at least 3 months, rated at least 3 out of 10 in intensity). Participants must not have recent experience with meditation or hypnosis, and should not be in other pain studies. Stable medication use and English fluency are required.

Inclusion Criteria

I am not in another chronic pain study and won't join one during this trial.
I have never taken a course in mindfulness or hypnosis.
I am 60 years old or older.
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo psychological treatments including Mindfulness Meditation, Therapeutic Hypnosis, or Story Listening, with sessions involving EEG and MRI assessments.

4 weeks
3 in-person sessions, 4 remote sessions

Follow-up

Participants are monitored for changes in pain intensity, pain unpleasantness, and other outcomes post-treatment.

1 week
1 in-person visit

What Are the Treatments Tested in This Trial?

Interventions

  • Mindfulness Meditation
  • Story Listening
  • Therapeutic Hypnosis

Trial Overview

The study compares three approaches: mindfulness meditation, therapeutic hypnosis, and story listening. Participants are randomly assigned to one group to see how these methods affect the brain and help manage chronic pain in older adults.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Therapeutic HypnosisExperimental Treatment1 Intervention
Group II: Story ListeningExperimental Treatment1 Intervention
Group III: Mindfulness MeditationExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Washington

Lead Sponsor

Trials
1,858
Recruited
2,023,000+

The University of Queensland

Collaborator

Trials
149
Recruited
71,700+

University of California, San Diego

Collaborator

Trials
1,215
Recruited
1,593,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+

University of Florida

Collaborator

Trials
1,428
Recruited
987,000+

Citations

Mindfulness Meditation for Chronic Pain: Systematic Review ...

We found low-quality evidence that mindfulness meditation is associated with a small decrease in pain compared with all types of controls in 30 RCTs.

Effectiveness of mindfulness meditation on the quality of life ...

This systematic review and meta-analysis found that mindfulness meditation significantly reduces pain intensity and improves quality of life in ...

Brain Scans Reveal that Mindfulness Meditation for Pain Is ...

Brain scans reveal that mindfulness meditation engages different neural pathways compared to placebo, demonstrating that pain relief from ...

Effectiveness of mindfulness meditation on pain and quality of ...

Results: The findings showed MBSR was effective in reduction of pain severity and the patients who practiced 8 sessions meditation reported significantly lower ...

Mindfulness Meditation for Chronic Pain

Mindfulness meditation was associated with a small effect of improved pain symptoms compared with control groups in a meta-analysis of 24 randomized controlled ...

Meditation: A Promising Approach for Alleviating Chronic Pain

Meditation may be used to manage chronic pain, which has several benefits, including pain alleviation, stress reduction, improved sleep, and general health.

The Effects of Mindfulness Meditation on Fibromyalgia ...

The purpose of this study is to examine the effects of a brief mindfulness meditation intervention on clinical and experimental pain in fibromyalgia (FM) ...

Mindfulness meditation for chronic pain: Systematic review ...

Purpose This study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults.