Surgical Methods for Broken Finger

(GRIP Trial)

KM
Overseen ByKatrina Munro, MHIS
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Spencer B Chambers
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines different surgical methods for fixing broken bones in the hand to determine which one promotes faster healing and easier recovery of hand movement. It compares three techniques: using thin metal pins without opening the skin (Closed Reduction and Percutaneous Pinning, or CRPP), placing a small screw inside the bone (Intramedullary Screw Fixation, or IMSF), and using a small incision to secure the bone with plates or screws (Open Reduction and Internal Fixation, or ORIF). The trial aims to identify the best method for helping patients return to daily activities with fewer complications. Individuals with hand fractures requiring surgery within 10 days of injury and meeting specific fracture criteria may be suitable for this trial. As an unphased trial, it offers a unique opportunity to advance surgical techniques for hand fractures.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these surgical methods are safe for treating broken fingers?

A previous study showed that CRPP (Closed Reduction and Percutaneous Pinning) reduces stiffness and causes less tendon irritation compared to some other methods, making it a well-tolerated option for fixing finger fractures. Patients reported good outcomes, with most regaining full motion in their fingers without major issues.

Research indicates that IMSF (Intramedullary Screw Fixation) is a safe and minimally invasive method with few complications. In one study, all patients experienced successful healing, and only a small number had major complications. Most patients were satisfied with the results and would choose this method again.

ORIF (Open Reduction and Internal Fixation) is also considered safe and effective. However, stiffness commonly occurs after this procedure. Despite this, many studies find it successful for stabilizing fractures and allowing early finger movement, which aids in a good recovery.

Overall, all three methods—CRPP, IMSF, and ORIF—are generally safe and have been effectively used to treat finger fractures, each with its own pros and cons regarding recovery and side effects.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to compare three different surgical methods for treating broken fingers, which could lead to improved recovery outcomes. Closed Reduction and Percutaneous Pinning (CRPP) is a less invasive option that involves using pins to hold the fracture in place without making a large incision, potentially reducing recovery time. Intramedullary Screw Fixation (IMSF) uses screws inserted into the bone, offering strong stabilization with minimal external hardware. Open Reduction and Internal Fixation (ORIF) involves a more direct access to the fracture site, allowing for precise alignment with the use of plates and screws. By comparing these techniques, researchers hope to determine which method provides the best balance of effectiveness and recovery for patients with finger fractures.

What evidence suggests that this trial's surgical methods could be effective for broken fingers?

This trial will compare different surgical methods for treating broken fingers. Closed Reduction and Percutaneous Pinning (CRPP) is one method under study, and studies have shown it often results in less stiffness and fewer tendon issues compared to Open Reduction and Internal Fixation (ORIF). ORIF, another method in this trial, provides good stability for healing, though it might cause stiffness. Intramedullary Screw Fixation (IMSF), also being tested, is praised for its reliable results, with many patients experiencing strong grip and a low chance of needing another surgery. Research indicates that IMSF can lead to faster recovery and a quicker return to work, with high patient satisfaction. Each method offers unique benefits, and the choice often depends on the specific type of fracture and the patient's needs.12367

Who Is on the Research Team?

SB

Spencer B Chambers

Principal Investigator

Western University

Are You a Good Fit for This Trial?

This trial is for people with broken bones in the hand (metacarpal or phalangeal fractures) who need surgery to fix them. It does not specify other inclusion or exclusion criteria, so it's likely for adults with these types of hand fractures.

Inclusion Criteria

I had surgery within 10 days after my injury.
MC arm: sagittal angulation in accordance with accepted norms (Table 1)
MC arm: shortening greater than 5mm, translation greater than 50%
See 6 more

Exclusion Criteria

I have had surgery for a fracture in my hand on the same side as my current issue.
Unable to read English, provide consent, or return to follow-up
I have an injury with tissue loss, tendon or nerve damage, infection, or shattered bone.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo surgical intervention using either IMSF, CRPP, or ORIF techniques for metacarpal or phalangeal fractures

6-8 weeks
Weekly visits for monitoring and adjustment

Follow-up

Participants are monitored for recovery, range of motion, grip strength, and complications

12 months
Monthly visits for assessments

Outcome Assessment

Final evaluation of patient recovery, satisfaction, and return to work

End of study at 12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Closed Reduction and Percutaneous Pinning (CRPP)
  • Intramedullary Screw Fixation (IMSF)
  • Open Reduction and Internal Fixation (ORIF)

Trial Overview

The study compares three surgical methods: intramedullary screw fixation (IMSF), closed reduction and percutaneous pinning (CRPP), and open reduction with internal fixation (ORIF). Patients are randomly assigned to a treatment based on their fracture type.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Open Reduction and Internal FixationExperimental Treatment1 Intervention
Group II: Intramedullary Screw FixationExperimental Treatment1 Intervention
Group III: Closed Reduction and Percutaneous PinningExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Spencer B Chambers

Lead Sponsor

Citations

Closed Reduction Percutaneous Pinning Versus Open ... - PMC

Traditionally, closed reduction percutaneous pinning (CRPP) resulted in decreased stiffness and tendon irritation compared to open reduction internal fixation ( ...

Closed Reduction Percutaneous Pinning Versus Open ...

Seven studies evaluated DASH scores; weighted average 7.6 for ORIF and 8.0 for CRPP. Tenolysis was performed at a rate of 10.3% for CRPP versus 13.4% for ORIF.

Early Functional Outcome of Closed Reduction and ...

This study evaluated the early functional outcomes of CRPP fixation for proximal phalangeal and metacarpal fractures done under conventional radiograph ...

Phalangeal fractures: A retrospective comparison of open ...

This study retrospectively compares characteristics of phalangeal fractures treated with closed reduction percutaneous pinning (CRPP) with those of fractures ...

Phalanx Finger CRPP and Phalanx ORIF in New Jersey

Closed reduction and percutaneous pinning of a finger (phalanx) fracture allows the fracture to be realigned and stabilized with metal wires (aka “pins”).

Closed reduction and percutaneous pinning of fractures ...

Early proximal interphalangeal joint motion was allowed and all patients achieved uneventful union, with an average total active motion of 265 degrees.

Phalangeal fractures: A retrospective comparison of open ...

This study retrospectively compares characteristics of phalangeal fractures treated with closed reduction percutaneous pinning (CRPP) with those of fractures ...