Caffeine for Cognitive Functioning
(GRANDMASTER Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will examine whether caffeine improves cognitive and competitive performance in professional chess players during tournament-style games. In a randomized double-blind crossover design, participants will complete two experimental sessions in which they consume either caffeinated coffee or decaffeinated coffee before playing a standardized chess match. Cognitive performance will be assessed using attention and reaction-time tests, including the Stroop Test, Trail Making Test, and Puzzle Rush task. Chess performance outcomes such as move accuracy, time management, and error rates will also be evaluated. The study aims to determine whether moderate caffeine intake enhances focus, alertness, and decision-making during prolonged competitive chess play.
Who Is on the Research Team?
Hossein Rafiei, PhD
Principal Investigator
St. Louis University
Are You a Good Fit for This Trial?
This trial is for male and female professional chess players aged 18-50, with a FIDE rating between 2300 and 2600 (or recently achieved this), who usually drink no more than two cups of coffee per day. Participants must be willing to follow study rules and give written consent.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Experimental Sessions
Participants complete two experimental sessions with caffeinated and decaffeinated coffee, followed by cognitive tests and chess games
Follow-up
Participants are monitored for cognitive and chess performance outcomes
What Are the Treatments Tested in This Trial?
Trial Overview
The study tests whether drinking caffeinated coffee versus decaf placebo before tournament-style chess games improves focus, reaction time, and decision-making in pro chess players. Each player tries both drinks in separate sessions; neither they nor the researchers know which one they're getting each time.
How Is the Trial Designed?
2
Treatment groups
Active Control
Placebo Group
Participants will consume one serving of black caffeinated coffee prepared from 15 g of ground coffee brewed in 200 g of water, providing approximately 100 mg of caffeine. The beverage will be consumed approximately 30 minutes before completion of cognitive testing and a standardized tournament-style chess game during the experimental visit.
Participants will consume one serving of black decaffeinated coffee prepared to match the caffeinated coffee in taste and appearance. The beverage will be consumed approximately 30 minutes before completion of cognitive testing and a standardized tournament-style chess game during the experimental visit.
Find a Clinic Near You
Who Is Running the Clinical Trial?
St. Louis University
Lead Sponsor
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