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Warning Labels for Cannabis Use

BR
AZ
Overseen ByAlexandra Zizzi, MSPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Wake Forest University Health Sciences
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests different warning labels on cannabis edibles. Researchers aim to understand how these labels influence consumer knowledge, perceived risk, and willingness to try the product. The trial examines various warning types, including text-only, text with icons, and labels detailing dose and side effects (such as Delayed Effects Plus Dose, Delayed Effects Plus Dose Plus Adverse Effects, Delayed Effects Plus Icon, and Delayed Effects Text Only). English-speaking residents of the United States who have not participated in a related study may qualify. As an unphased trial, this study provides a unique opportunity to contribute to important research on consumer safety and product labeling.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that these warning labels are safe for use with cannabis edibles?

Research shows that consuming cannabis edibles takes longer to produce effects compared to smoking. This delay might lead some people to consume more, mistakenly believing they haven't had enough. Overconsumption can cause temporary issues like anxiety, paranoia, or feeling unexpectedly high.

Studies have found that edibles pose both mental and physical health risks, including a fast heartbeat, sweating, and impaired decision-making. However, when used carefully and in small amounts, edibles are generally safe. Knowing the right dosage and waiting for the effects to begin is crucial.

The warnings on packaging, tested in this study, aim to help users make informed choices and avoid these risks. By providing clear information about delayed effects, dosing, and possible side effects, the goal is to enhance safety and prevent overconsumption.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how different warning labels on cannabis edibles might impact consumer awareness and behavior. Unlike current labeling practices that often lack detailed information, this trial examines labels that include messages about delayed effects, dosing instructions, and potential adverse effects. Some labels even feature icons to make the information more accessible. The goal is to find out which type of warning is most effective in helping consumers make safer choices, ultimately enhancing public health and safety.

What evidence suggests that this trial's warnings could be effective for cannabis use?

This trial will compare different warning label strategies for cannabis edibles. Research has shown that cannabis edibles can take 30 to 120 minutes to start working, with effects lasting between 6 to 12 hours. In this trial, one group will receive a package without a warning message, while other groups will receive packages with various warning labels. These labels may include dosing information, warnings about side effects, and icons or text about delayed effects. Studies have found that such warnings help users understand potential risks, like the delayed start and long-lasting effects. Overall, these warning strategies aim to increase consumer awareness of the risks and promote safer choices when using cannabis edibles.12367

Who Is on the Research Team?

BR

Beth Reboussin, PhD

Principal Investigator

Wake Forest University Health Sciences

Are You a Good Fit for This Trial?

This study is for English-speaking adults living in the United States who have not already taken part in a related earlier project. Participants are selected to ensure a mix of different backgrounds and cannabis use habits.

Inclusion Criteria

I can speak and understand English.
United States resident

Exclusion Criteria

Already participated in a precursor project (IRB00104038, IRB000111438)
Eligible but demographic and user group strata have already been met

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Experiment

Participants are assigned to view cannabis edibles packaging with different warning variations and answer questions to assess perceptions and willingness to try the product

1 day
1 visit (in-person)

Follow-up

Participants are monitored for their recall and perception of the warnings after the experiment

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Delayed Effects Plus Dose
  • Delayed Effects Plus Dose Plus Adverse Effects
  • Delayed Effects Plus Icon
  • Delayed Effects Text Only
  • No Warning Control

Trial Overview

The trial compares different warning labels on cannabis edibles, including text about delayed effects, icons, dose information, and adverse effects. It looks at how these warnings affect knowledge, perceived harm, and willingness to try edibles.

How Is the Trial Designed?

5

Treatment groups

Experimental Treatment

Group I: No Warning ControlExperimental Treatment1 Intervention
Group II: Delayed Effects Text OnlyExperimental Treatment1 Intervention
Group III: Delayed Effects Plus IconExperimental Treatment1 Intervention
Group IV: Delayed Effects Plus Dose Plus Adverse EffectsExperimental Treatment1 Intervention
Group V: Delayed Effects Plus DoseExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials
1,432
Recruited
2,506,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

Tasty THC: Promises and Challenges of Cannabis Edibles

This paper explores the current state of research regarding edibles, highlighting the promises and challenges that edibles present to both users and policy ...

Marijuana Edibles: Risks, Side Effects & Dangers

The effects of marijuana edibles last much longer than smoking, usually up to several hours depending on the amount of THC consumed.

Effects of cannabis edible advertising messages and ...

... marijuana. Concerns and dislikes about edibles included delayed effects, unexpected highs, the unpredictability of the high, and ...

How Long Do Cannabis Edibles Last?

A cannabis edible high can last from 6 to 8 hours depending on how much you take, your metabolism, and more. Learn more about edible effects ...

Edible Cannabis Affects People Differently 'start low

į Clear your schedule – the effects from edible cannabis last 4 to 12 hours with some effects lasting up to 24 hours į Label and store all cannabis securely.

THC Warning Labels: Compliance Made Simple

You also usually need safety cautions such as impairment, age restrictions, pregnancy and breastfeeding risks, and delayed effects for edibles. Always confirm ...

How Cannabis Use Impacts Long-Term Health

An emergency medicine physician discusses the impact of marijuana on your health, whether it's used recreationally or medicinally.