Ischemic Conditioning + Neuromuscular Electrical Stimulation for Lower Limb Amputation
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this clinical trial is to learn if ischemic conditioning and neuromuscular electrical stimulation improves muscle strength and walking behavior in those with limb loss. The main questions this trial aims to answer are:
Does neuromuscular electrical stimulation improve muscle strength and gait behavior in people who have a leg amputation?
Does neuromuscular electrical stimulation boost the effects of ischemic conditioning on muscle strength and gait behavior in people who have a leg amputation?
Researchers will compare the effects of neuromuscular electrical stimulation to ischemic conditioning to see if there are any significant differences between the impacts of each intervention. Also, researchers will use both interventions together to see if the interventions can boost each other's positive impacts on walking and function in people with leg amputation.
Participants will:
* Do ischemic conditioning OR neuromuscular electrical stimulation OR both interventions at home every other day for 2 weeks
* Visit the laboratory before and after completing interventions for the tests
* Visit the laboratory one week after the post intervention visit for follow-up tests
Are You a Good Fit for This Trial?
This trial is for adults who have had an above-knee or below-knee leg amputation. Participants should be able to do home-based exercises and attend lab visits before, after, and one week following the intervention period.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Ischemic Conditioning
- Neuromuscular Electrical Stimulation
Trial Overview
The study tests whether using a blood pressure cuff (for ischemic conditioning), neuromuscular electrical stimulation, or both can improve muscle strength and walking in people with leg amputations. Participants are assigned to different groups for two weeks of at-home treatment.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Illinois at Chicago
Lead Sponsor
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