Aloe Vera Mouthwash for Mouth Sores

Not yet recruiting at 2 trial locations
TA
JH
Overseen ByJeanne Hlebichuk, PhD, RN, NE-BC, LSS Black Belt
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Wake Forest University Health Sciences
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this quasiexperimental cohort controlled intervention study is to learn if aloe vera mouthwash works better than usual care in the prevention and treatment of oral mucositis. Researchers will compare aloe vera to usual care. Participants in the intervention group will rinse their mouths with aloe vera 4 x/day for 28 days of their treatment. They will also complete questionnaires about oral health and mucositis.

Who Is on the Research Team?

TA

Tara Albrecht, PhD, ACNP-BC, ACHPN, RN

Principal Investigator

Advocate Health

Are You a Good Fit for This Trial?

This trial is for adults with blood cancers like acute leukemia who are at risk of developing mouth sores (oral mucositis) during their treatment. Participants must be able to use a mouthwash and complete questionnaires.

Inclusion Criteria

Access to a personal email address to support study participation
English speaking/reading without an interpreter
I have acute leukemia and am currently receiving chemotherapy.

Exclusion Criteria

Allergy to Aloe Vera
I am able to understand and agree to participate in the study.
Transplant patients
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Aloe Vera Mouthwash

Trial Overview

The study compares rinsing with aloe vera mouthwash four times daily for 28 days versus standard care, to see which better prevents or treats mouth sores in people undergoing treatment for blood cancers.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Phase 2 InterventionExperimental Treatment1 Intervention
Group II: Phase 1 Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials
1,432
Recruited
2,506,000+