Virtual Reality Cognitive Intervention for ICU Delirium

This trial explores whether virtual reality (VR) games can improve memory, attention, and mood in individuals who have survived an ICU stay. Participants will use a VR headset and hand controls at home to engage in either VR-based attention control activities or a VR-based cognitive training program. It suits English-speaking adults over 50 who were in the ICU for breathing problems and experienced delirium, a temporary confusion that occurs in some hospital patients. As an unphased trial, this study allows participants to contribute to innovative research that could enhance recovery experiences for future ICU survivors.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that virtual reality (VR) cognitive training programs are generally safe for ICU patients. One study confirmed that VR training is both feasible and safe for ICU patients, including those on breathing machines, indicating that the treatment is usually well-tolerated. Another review found that VR can help reduce confusion in ICU patients without causing major issues. Although specific side effect data is limited, current research supports the safety of VR-based treatments in similar situations.¹²³⁴⁵

Researchers are excited about using virtual reality (VR) for treating ICU delirium because it offers a completely new approach compared to traditional methods like medication or environmental adjustments. Unlike standard treatments, the VR-based cognitive training program actively engages patients in immersive experiences that can stimulate their cognitive functions and attention. This innovative method could potentially enhance recovery by directly targeting brain activity, offering a non-invasive and engaging alternative to conventional care. Moreover, the VR-based attention control serves as a placebo comparator, helping researchers discern the specific benefits of cognitive training within the virtual environment.

Research has shown that virtual reality (VR) can enhance mental functions in individuals who have been in the ICU. One study with 46 ICU patients found that using VR for seven days reduced stress, pain, and anxiety while improving cognitive skills. Another study discovered that VR can enhance both short-term and long-term memory in seriously ill patients. This trial will compare two VR-based interventions: a VR-based attention control and a VR-based cognitive training program. VR appears promising for providing mental exercises that could improve memory, focus, and mood for those recovering from intensive care. These findings suggest that VR-based programs might assist ICU survivors in managing the mental and emotional challenges they encounter after leaving the hospital.¹²⁵⁶⁷