Mediterranean vs. Fermented Food Diets for Lupus

This trial aims to assess how well individuals with lupus (an autoimmune disease where the body attacks its own tissues) can adhere to either a Mediterranean diet or a high-fermented-food diet over four months. Researchers seek to determine the practicality and ease of following these diets for lupus patients. Those diagnosed with lupus and receiving medical care for it might be suitable candidates. Participants should not have allergies to gluten, soy, or cow's milk, and should not currently follow a vegetarian or vegan diet. As an unphased trial, this study offers a unique opportunity to contribute to research that may enhance dietary recommendations for lupus patients.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research shows that the Mediterranean diet is likely safe for people with lupus. Studies have found that those who follow this diet closely often have a lower chance of developing lupus. It also helps manage the disease and improve heart health in those who already have lupus. No major safety concerns have been reported for this diet.

Evidence suggests that a high fermented food diet might help reduce inflammation and support overall immune health. This diet includes foods like yogurt and kimchi, which benefit gut health. Research has not identified any specific safety risks for this diet either.

Researchers are excited about these dietary approaches for lupus because they offer a natural, food-based strategy that could complement or even reduce the need for medications like corticosteroids and immunosuppressants, which often come with significant side effects. The Mediterranean diet is rich in anti-inflammatory foods like fruits, vegetables, and healthy fats, which might help manage lupus symptoms by reducing inflammation in the body. On the other hand, a high fermented food diet could improve gut health and boost the immune system by introducing beneficial probiotics. These dietary patterns offer a holistic way to potentially manage lupus, tapping into the body's natural processes rather than solely relying on pharmaceutical interventions.

This trial will compare the effects of a Mediterranean diet with a high fermented food diet for individuals with lupus. Studies have shown that a Mediterranean diet can lower the risk of developing systemic lupus erythematosus (SLE) and may reduce disease activity by fighting inflammation. This diet includes omega-3 fatty acids, which help reduce inflammation, a key issue in lupus. While the Mediterranean diet won't cure lupus, it can improve some symptoms and boost overall health.