Nurse-Led PrEP Initiation for HIV Prevention

(SWIFT Trial)

SR
EA
Overseen ByEvan Ames
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Rhode Island Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

PrEP is a medication that can help prevent the spread of HIV, but many who might benefit from PrEP do not take it. Individuals experiencing incarceration are interested in starting PrEP while incarcerated, but there are challenges that make it difficult for them to start this medication when they return to the community. This study will test to see if a nurse-led, same-day PrEP start program can help individuals experiencing incarceration start and stay on PrEP. To do this, N = 90 PrEP-eligible patients during their incarceration will test the nurse-led program. Everyone will receive access to a nurse-led behavioral intervention during incarceration and information about PrEP services available in the community. Then, N = 60 participants will receive patient navigation support to help them link with PrEP care in the community and N = 30 participants will receive a list of community resources. Research interviews will be conducted with participants while they are incarcerated and 1, 3, and 6 months after they re-enter the community. Participants are offered compensation for each of the research interviews.

Who Is on the Research Team?

SR

Susan Ramsey, PhD

Principal Investigator

Rhode Island Hospital

Are You a Good Fit for This Trial?

This trial is for people who are currently incarcerated and are eligible to take PrEP, a medication that helps prevent HIV. Participants should be interested in starting PrEP during incarceration and planning to return to the community soon.

Inclusion Criteria

Currently incarcerated at the Rhode Island Department of Corrections
Report any criminalized drug use or at least one heavy drinking day in the 90 days prior to incarceration
Likely to be incarcerated for more than a week but less than 6 months
See 6 more

What Are the Treatments Tested in This Trial?

Interventions

  • Nurse-Led Intervention
  • Patient Navigation Intervention

Trial Overview

The study compares a nurse-led program that starts PrEP while incarcerated with standard care. Some participants also get extra help connecting to community services after release, while others receive only resource lists.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Experimental ArmExperimental Treatment2 Interventions
Group II: Control ArmActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Rhode Island Hospital

Lead Sponsor

Trials
275
Recruited
71,400+