150 Participants NeededMy employer runs this trial

Suction vs Water Seal for Collapsed Lung

(SUS-HPTX Trial)

KE
Overseen ByKelsey Evans, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Vanderbilt University Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine whether a suction or water seal method better manages chest tubes in trauma patients with a collapsed lung and blood in the chest (hemopneumothorax or hemothorax). The study will compare the duration of chest tube placement and any complications associated with each method. Participants will join either the suction or water seal group based on their enrollment month. This trial may suit individuals admitted for a chest injury requiring a chest tube. The goal is to improve treatment practices and ensure quick and safe patient recovery. As an unphased trial, it offers participants the chance to contribute to valuable research that could enhance future treatment options.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these chest tube management strategies are safe for trauma patients?

Previous studies have found both suction and water seal methods to be generally safe for treating a collapsed lung. Research shows that suction can safely accelerate healing without causing major problems. Although some people worry about tissue damage, studies indicate it is usually safe when performed carefully.

Conversely, the water seal method is as safe and effective as low suction. It often results in shorter durations with the chest tube in place, allowing many patients to spend less time in the hospital.

In summary, both methods are safe and effective, with slight differences in the duration of chest tube placement.12345

Why are researchers excited about this trial?

Researchers are excited about the trial comparing suction and water seal techniques for treating a collapsed lung because these methods could offer new insights into improving patient outcomes. While traditional treatments often involve just monitoring or surgery, suction might actively remove air more efficiently from the pleural space, potentially speeding up recovery. On the other hand, the water seal method could provide a simpler and less invasive alternative, reducing the risk of additional complications. By evaluating these techniques head-to-head, the trial aims to determine which method is more effective, safer, and faster, potentially changing how collapsed lungs are managed in the future.

What evidence suggests that this trial's treatments could be effective for collapsed lung?

This trial will compare the effectiveness of suction versus water seal for treating a collapsed lung. Research has shown that the water seal method might be more effective than suction for this condition. The SEAL IT Trial found that using a water seal led to shorter chest tube use without increasing complications. Another study indicated that patients using the water seal experienced shorter air leak times, allowing their lungs to heal faster. Conversely, suction can resolve a pneumothorax (air leakage between the lung and chest wall) more quickly, but it may prolong air leaks and chest tube use. Both methods are standard treatments, and studies suggest that the water seal can be as safe and effective as suction in reducing air leaks and hospital stay length. Participants in this trial will be assigned to either the suction or water seal treatment arm based on the month of enrollment.12345

Are You a Good Fit for This Trial?

This trial is for trauma patients who have blood and/or air in their chest (hemothorax or hemopneumothorax) and need a chest tube. Participants must be admitted to the trauma service.

Inclusion Criteria

* Admitted to trauma service
I currently need a chest tube for bleeding or air in my chest.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive chest tube management with either suction or water seal based on randomization

Duration varies based on clinical decision
Continuous monitoring during hospital stay

Follow-up

Participants are monitored for safety and effectiveness after treatment, including assessment of readmissions and subsequent thoracic interventions

30 days
Follow-up assessments up to 30 days post-discharge

What Are the Treatments Tested in This Trial?

Interventions

  • Suction
  • Water Seal

Trial Overview

The study compares two ways of managing chest tubes: using suction versus an underwater seal, to see which method leads to faster removal of the tube and fewer complications. Patients are assigned by month, with doctors able to adjust treatment if needed.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Odd monthsExperimental Treatment1 Intervention
Group II: Even monthsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Vanderbilt University Medical Center

Lead Sponsor

Trials
922
Recruited
939,000+

Citations

The impact of suction duration on lung collapse during one ...

This is consistent with previous research showing that shorter suction durations (e.g., 30–60 s) can achieve similar outcomes in terms of lung ...

Water Seal vs. Suction for Collapsed Lung (SEAL IT Trial)

Studies suggest that a water seal can be as safe and effective as low suction in reducing air leaks and shortening the duration of chest tube use. In one study, ...

Comparison of efficacy and safety of different suction pressure ...

The bronchial suction has been applied in speeding lung collapse. Low suction pressure may not speed lung collapse, but high pressure causes ...

A trial of suction for the early resolution of a collapsed lung

In terms of benefits, those randomly assigned to suction may resolve their pneumothorax more quickly and hence a shorter hospital stay. When the study is ...

safety-of-suction-in-management-of-pneumothorax-a- ...

Resolution of a pneumothorax may be aided by the use of negative pressure suction applied to an underwater seal drain. This method has long been.