Pharmacist-Assisted Therapy for Heart Failure

(PATRIOT-HF Trial)

PL
LL
Overseen ByLexus L Ujano-De Motta, BS
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a virtual collaboration between pharmacists and cardiologists can improve medication prescriptions for Veterans with heart failure. The goal is to ensure Veterans receive the appropriate heart medications, which can extend their lives, reduce hospital visits, and improve overall well-being. Veterans hospitalized with heart failure in the last three months who are not on optimal heart medications might be suitable candidates for this study. As an unphased trial, it offers Veterans the chance to contribute to innovative care strategies that could enhance their treatment experience.

What prior data suggests that this pharmacist/cardiologist virtual team digital consultation is safe for Veterans with heart failure?

A previous study showed that virtual consultations with pharmacists and cardiologists are generally safe for patients. During these digital consultations, healthcare professionals review patient records and provide treatment advice. This method focuses on improving the prescription of current medications, so no new drugs are tested, which typically results in fewer safety concerns. Additionally, the virtual consultation itself poses little risk to patients, as it aims to enhance the care Veterans already receive.12345

Why are researchers excited about this trial?

Researchers are excited about the Pharmacist/Cardiologist Virtual Team Digital Consultation because it brings a fresh approach to managing heart failure. Unlike traditional care, which often relies solely on in-person doctor visits, this method uses a digital consultation platform that combines the expertise of both pharmacists and cardiologists. This team works together virtually to ensure that veterans with heart failure receive tailored, guideline-driven care, both during their hospital stay and after discharge. The use of digital consultations not only enhances coordination and follow-up care but also focuses on educating patients, empowering them to take charge of their health. This innovative approach could lead to better outcomes by ensuring patients are receiving optimal therapy and support.

What evidence suggests that this pharmacist/cardiologist virtual team consultation is effective for heart failure?

This trial will compare the effectiveness of a Pharmacist/Cardiologist Virtual Team with usual care for heart failure patients. Research has shown that a virtual team of pharmacists and cardiologists can enhance heart failure treatment. Studies have found that pharmacist involvement leads to more effective use of crucial heart medications, helping patients live longer and avoid hospital visits. Specifically, one study found that this approach improved the use of key heart medications compared to care without pharmacists. Another study demonstrated that patients with heart failure benefited from this method, proving it safe and effective. Overall, a virtual care team ensures patients receive the right medications in the right amounts.678910

Who Is on the Research Team?

PL

Paul L Hess, MD MS

Principal Investigator

Rocky Mountain Regional VA Medical Center, Aurora, CO

Are You a Good Fit for This Trial?

This trial is for Veterans with heart failure who are being treated at VA medical centers. Participants should be hospitalized or recently discharged and need help getting the right heart failure medications and doses.

Inclusion Criteria

Primary study cohort consists of patients admitted to a VA medical center
Left ventricular ejection fraction ≤ 40%
Secondary study cohort consists of patients admitted to VA-paid community hospitals
See 3 more

Exclusion Criteria

I have unstable blood pressure or heart function.
I am only receiving comfort care or am in hospice.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Pharmacist and cardiologist team provides digital consultation to improve heart failure medication prescribing

14 days
Virtual consultations

Follow-up

Participants are monitored for safety and effectiveness after intervention

90 days
Outpatient follow-up facilitated

Implementation

Implementation of intervention at VA medical centers in a stepped-wedge design

6 months per wave

What Are the Treatments Tested in This Trial?

Interventions

  • Pharmacist/Cardiologist Virtual Team Digital Consultation

Trial Overview

The study tests if a virtual team of pharmacists and cardiologists can work together to review patient records and advise doctors on how to best prescribe heart failure medicines, aiming to improve care after hospital stays.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Pharmacist/Cardiologist Virtual Team (Intervention)Experimental Treatment1 Intervention
Group II: Usual Care (Control Period)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+

Citations

Digital solutions to optimize guideline-directed medical ... - PMC

Virtual peer-to-peer consultation is an example of a digital consultation used to evaluate the efficacy to optimize GDMT prescription rate for ...

Digital Solutions to Optimize Guideline-Directed Medical ...

Digital solutions have the potential to support medical professionals to optimize GDMT prescriptions in a growing HF population. We aimed to ...

Outcomes of a hybrid heart failure clinic model on ...

The hybrid model involving pharmacists was associated with greater initiation of GDMT compared to in-person care without a pharmacist. This study confirms the ...

Guided Management of Hospitalized Heart Failure Patients ...

In patients hospitalized with HFrEF, a virtual care team-guided GDMT optimization strategy was safe and effective across multiple hospitals ...

Guideline-Directed Medical Therapy for Heart Failure

Clinical trials have shown that patients with heart failure with reduced ejection fraction (HFrEF) benefit from guideline-directed medical therapy (GDMT) ...

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