Peripheral Venous Pressure Measurements for Heart Failure

KA
Overseen ByKhawaja Ammar, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Wake Forest University Health Sciences
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if daily checks of peripheral venous pressure (pressure in the veins) can shorten hospital stays and reduce rehospitalization for people with congestive heart failure. Participants will either have their vein pressure measured daily or receive standard care without these measurements. The trial is ideal for those who have had congestive heart failure for at least three months, are currently experiencing worsening symptoms, and are admitted to Aurora St. Luke's Medical Center. Participants must be English-speaking and already have a peripheral IV line inserted.

As an unphased trial, this study offers a unique opportunity to contribute to research that could improve future heart failure care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that peripheral venous pressure measurements are safe for heart failure patients?

Research shows that measuring peripheral venous pressure (PVP) is safe for patients. Studies have found that PVP closely matches central venous pressure and can be measured easily without surgery or complex procedures.

No direct evidence indicates harmful effects from PVP measurements. Studies have not reported any significant side effects, suggesting that patients generally tolerate it well.

Doctors also use PVP to assess heart health at the bedside, further supporting its safety in clinical settings. For those considering joining a trial involving PVP, research suggests it is a safe way to monitor heart health.12345

Why are researchers excited about this trial?

Researchers are excited about peripheral venous pressure measurements for heart failure because this technique could offer a more immediate way to monitor patient status. Unlike standard care, which relies on less frequent assessments, these measurements provide daily updates to physicians. This frequent data could lead to quicker and more tailored treatment decisions, potentially improving patient outcomes by catching issues earlier.

What evidence suggests that peripheral venous pressure measurements are effective for heart failure?

Research has shown that measuring peripheral venous pressure (PVP) closely relates to central venous pressure (CVP), which is crucial for patients with heart failure. Studies indicate that PVP can enhance bedside assessment of heart problems. This trial will compare two approaches: one group will receive daily PVP measurements provided to physicians, while the other group will receive standard clinical care without daily PVP measurements. This method promises a simpler way to check heart stress without invasive procedures. Early evidence suggests that using PVP measurements may reduce hospital stays and readmission rates, making it a potentially effective tool for managing congestive heart failure.12346

Who Is on the Research Team?

KA

Khawaja Ammar, MD

Principal Investigator

Wake Forest University Health Sciences

Are You a Good Fit for This Trial?

This trial is for English-speaking patients with a history of Congestive Heart Failure for at least 3 months, who are admitted to Aurora St. Luke's Medical Center due to worsening symptoms.

Inclusion Criteria

* English speaking only
I have had Congestive Heart Failure for at least 3 months and was admitted to Aurora St. Luke's for worsening symptoms.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either standard clinical care or peripheral venous pressure-guided therapy during hospitalization

up to 8 days
Daily in-hospital monitoring

Follow-up

Participants are monitored for rehospitalization and other outcomes post-discharge

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Peripheral Venous Pressure Measurements

Trial Overview

The study is testing if daily measurements of peripheral venous pressure can reduce the hospital stay and rehospitalization rates in heart failure patients compared to standard care without these daily measurements.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: peripheral venous pressure measurementsExperimental Treatment1 Intervention
Group II: standard clinical careActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials
1,432
Recruited
2,506,000+

Citations

Peripheral Venous Pressure Measurements in Patients ...

In patients with acute heart failure syndromes, a simple assessment of PVP demonstrates a high correlation with CVP.

Peripheral venous pressure measurements to evaluate ... - PMC

PVP measured via peripheral venous access strongly correlates with invasively obtained RAP. PVP measurements may improve current bedside assessments of ...

Peripheral Venous Pressure (PVP) Randomized Clinical Trial

The purpose of the study is to determine if there is a reduction in the length of stay and rates of rehospitalization for patients diagnosed ...

Peripheral Venous Pressure Measurements to Evaluate ...

Discussion. The present study confirms the strong correlation between PVP and invasively obtained RAP in the patients with cardiac diseases. · Conclusion.

Association between early central venous pressure ...

Early CVP measurement (within 5 h) demonstrated an independent correlation with a decrease in both immediate and extended all-cause mortality ...

6.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/35511694/

Association of peripheral venous pressure with adverse ...

We examined the association between PVP before discharge and post-discharge outcomes in hospitalized patients with acute HF.