75 Participants Needed

Caffeinated Beverages for Caffeine Intake

VP
AI
Overseen ByAlethios, Inc.
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how different caffeinated drinks affect people's feelings and bodily responses. Participants will try three types of drinks: a regular caffeinated drink, a low-sugar caffeinated drink, and a non-caffeinated drink for comparison. It suits adults who regularly consume sweetened caffeine drinks and are willing to switch to the test drinks. Ideal candidates maintain a stable health routine and use a wearable device to track their responses. As an unphased trial, this study allows participants to contribute to understanding caffeine's effects on daily life.

Do I need to stop taking my current medications for the trial?

The trial requires that you do not use any medications or dietary supplements containing caffeine or that interact with caffeine. If you are on any unstable prescription medication, you may not be eligible to participate.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that caffeine is generally safe for most healthy adults. Studies have found that consuming up to 400 milligrams of caffeine per day usually does not link to health problems. This amount equals about four cups of brewed coffee or 10 cans of cola. The caffeinated drinks tested in the trial fall within this safe range.

While caffeine is safe in moderation, it can affect individuals differently. Some people might feel jittery or have trouble sleeping if sensitive to caffeine. In rare cases, very high amounts can cause serious side effects like seizures or vomiting, but these amounts far exceed typical consumption.

Overall, the caffeinated drinks in this study are likely well-tolerated by most people. It is important to monitor total caffeine intake and its personal effects.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about this trial because it's exploring how different caffeinated beverages impact caffeine intake, which is a bit different from standard energy drinks or coffee. The trial includes a caffeinated beverage and a low sugar, caffeinated option, offering a potentially healthier alternative for those who want to reduce sugar intake without giving up caffeine. This could lead to new, less sugary options for caffeine consumers, which is particularly appealing in the context of growing health consciousness surrounding sugar consumption. Plus, by comparing these to a control beverage, researchers can better understand the actual effects of caffeine versus other factors in these drinks.

What evidence suggests that this trial's treatments could be effective for caffeine intake?

This trial will compare the effects of different caffeinated beverages. Research has shown that caffeinated drinks can offer health benefits. Specifically, studies suggest that regularly drinking coffee might reduce the risk of developing type 2 diabetes by up to 60%. Caffeine can also help people with asthma breathe more easily by opening their airways. However, caffeine may increase blood pressure and heart rate. Generally, drinking caffeinated coffee in moderation is linked to positive health effects. Participants in this trial will receive either a caffeinated beverage, a caffeinated low-sugar beverage, or a control beverage to assess these effects.678910

Who Is on the Research Team?

KN

Kristin Nieman, PhD

Principal Investigator

Nlumn LLC

Are You a Good Fit for This Trial?

This trial is for generally healthy adults who want to participate in a study evaluating the effects of different caffeinated beverages on well-being. Specific eligibility criteria are not provided, but typically participants should not have conditions that could be affected by caffeine.

Inclusion Criteria

I am willing to use my smartphone, tablet, or computer with internet for the study.
My BMI is between 18.5 and 35.
I am willing to replace my daily caffeine with the study's beverage.
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants consume caffeinated or control beverages and are monitored for subjective and physiological responses

5 days
Daily visits (in-person or virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Caffeinated beverage
  • Caffeinated, low sugar beverage
  • Control beverage

Trial Overview

The study is testing how three types of beverages—a regular caffeinated beverage, a low-sugar caffeinated beverage, and a control (non-caffeinated) beverage—affect individuals' subjective feelings and physiological responses after consumption.

How Is the Trial Designed?

3

Treatment groups

Active Control

Placebo Group

Group I: Caffeinated, low sugar beverageActive Control1 Intervention
Group II: Caffeinated beverageActive Control1 Intervention
Group III: Control beveragePlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.

Lead Sponsor

Nlumn LLC

Collaborator

Alethios, Inc.

Collaborator

Citations

Caffeine Consumption Patterns, Health Impacts, and Media ...

Caffeine has also been shown to provide relief for asthmatic patients by dilating airways, thus facilitating easier breathing [50].

Caffeinated Beverage Survey

Caffeine intake was highest in consumers aged 50–64 years and lowest in children aged 2-5. Coffee was the largest contributor (69%) to caffeine intake across ...

Caffeinated Coffee Consumption and Health Outcomes in the ...

This study confirms the beneficial health effects of caffeinated coffee consumption in the US population on the health outcomes considered, and quantifies ...

Caffeinated Beverages—Unveiling Their Impact on Human ...

Existing studies indicate that regular coffee consumption can reduce the probability of type 2 diabetes mellitus by 60% for both caffeinated and decaffeinated ...

Acute Effects of Coffee Consumption on Health among ...

The consumption of caffeinated coffee was associated with 58 daily premature atrial contractions as compared with 53 daily events on days when caffeine was ...

Spilling the Beans: How Much Caffeine is Too Much?

For most adults, the FDA has cited 400 milligrams* a day — that's about two to three 12-fluid-ounce cups of coffee — as an amount not generally ...

Caffeine: How much is too much?

Up to 400 milligrams (mg) of caffeine a day seems safe for most adults. That's about the amount of caffeine in four cups of brewed coffee, 10 cans of cola or ...

The Safety of Ingested Caffeine: A Comprehensive Review

We report that, for healthy adults, caffeine consumption is relatively safe, but that for some vulnerable populations, caffeine consumption could be harmful.

9.

nutritionsource.hsph.harvard.edu

nutritionsource.hsph.harvard.edu/caffeine/

Caffeine - The Nutrition Source

Consuming 10-14 grams at one time is believed to be fatal. Caffeine intake up to 10 grams has caused convulsions and vomiting, but recovery is ...

Energy Drink Research & Science | American Beverage ...

It is safe for the general adult population to consume two servings of energy drinks per day with no health consequences.