Bifidobacterium adolescentis for Healthy Aging
(VITAL Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether a probiotic supplement called Bifidobacterium adolescentis iVS-1 can improve markers of aging and overall health in adults. Researchers aim to determine if altering the gut microbiome (the community of bacteria in the stomach) can positively affect health as people age. Participants will take either the probiotic or a placebo (a pill with no active ingredients) to compare results. Ideal participants are individuals aged 40 to 75 who do not have chronic diseases and are not currently using probiotics or similar supplements. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research on aging and gut health.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are using probiotics, prebiotics, or metabolic-altering supplements.
Is there any evidence suggesting that Bifidobacterium adolescentis (iVS-1) is safe?
Research has shown that Bifidobacterium adolescentis (iVS-1) is generally safe for people. Some studies found that iVS-1 helps maintain a healthy gut lining, which suggests safety and may reduce unwanted side effects.
Further research on Bifidobacterium species, including iVS-1, indicates they are well-tolerated, meaning most people do not experience major side effects when taking this probiotic.
While individual responses can vary, the available data suggests that iVS-1 is safe for human use. Prospective trial participants should find this information encouraging. Always consult a healthcare provider before joining any study to ensure it is appropriate.12345Why are researchers excited about this trial?
Most treatments for healthy aging focus on lifestyle changes and medications that manage age-related conditions. But Bifidobacterium adolescentis iVS-1 is unique because it's a probiotic capsule that aims to promote healthy aging directly through gut health. This treatment introduces beneficial bacteria that may support digestion, boost the immune system, and enhance overall well-being. Researchers are excited about its potential to offer a natural, non-invasive alternative to traditional aging treatments, focusing on maintaining health from the inside out.
What evidence suggests that Bifidobacterium adolescentis (iVS-1) might be an effective treatment for healthy aging?
Studies have shown that Bifidobacterium adolescentis, a type of probiotic, can promote healthy aging by boosting the immune system, producing vitamins, and enhancing mood and sleep. Research also suggests that this probiotic may support bone health and reduce the risk of age-related diseases. It alters gut bacteria, potentially influencing the aging process. Early findings indicate that Bifidobacterium adolescentis can improve overall health and function. These benefits could contribute to healthier aging and improved well-being.13467
Are You a Good Fit for This Trial?
This trial is for midlife adults who are interested in healthy aging. Participants should be generally healthy without any major medical conditions that could interfere with the study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Bifidobacterium adolescentis (iVS-1) or placebo once daily for 150 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Bifidobacterium adolescentis (iVS-1)
Trial Overview
The trial is testing if a probiotic called Bifidobacterium adolescentis iVS-1 can improve markers of biological aging, metabolic health, and functional outcomes compared to a placebo. It's randomized and double-blind, meaning neither participants nor researchers know who gets the real probiotic or placebo.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Probiotic Capsule
Placebo capsule
Find a Clinic Near You
Who Is Running the Clinical Trial?
Synbiotic Health
Lead Sponsor
MusB Research
Collaborator
Citations
iVS-1 Probiotic Intervention Targeting Biological Aging in ...
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis ...
The role of Bifidobacterium in longevity and the future ... - PMC
This review explores the role and health impacts of probiotics, focusing specifically on Bifidobacterium spp.
Experience Healthy Aging with B. adolescentis
Collectively, they support a healthy immune system, produce vitamins, help improve mood and sleep, promote bone health, and reduce disease risk. Importantly, ...
Effect of Bifidobacterium Adolescentis on Aging in Healthy ...
This study will include middle-aged and elderly people aged 45-65 years to carry out the translational study of Bifidobacterium adolescentis, and design a ...
iVS-1 Probiotic Intervention Targeting Biological Aging ...
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis ( ...
iVS-1
adolescentis iVS-1. Further studies confirmed its stability, safety and efficacy, including a clinical trial showing iVS-1 improved gut barrier function.
NCT07408518 | Impact of B. Adolescentis iVS-1 Probiotic ...
The study aims to evaluate the probiotic's effects not only on gastrointestinal symptoms but also on secondary outcomes like sleep disturbance, ...
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