Alcohol Sensitivity for Healthy Adults

SJ
BL
Overseen ByBen Lewis, PhD
Age: 65+
Sex: Any
Trial Phase: Academic
Sponsor: University of Florida

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80. Participants will complete two sessions during which they will complete questionnaires and laboratory measures of mental abilities and brain activity and receive a beverage that may or may not contain a moderate dose of alcohol.

Who Is on the Research Team?

SJ

Sara Jo Nixon, PhD

Principal Investigator

University of Florida

BL

Ben Lewis, PhD

Principal Investigator

University of Florida

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 65 to 80 who currently drink alcohol. Participants should not have any major health issues that would prevent safe participation.

Inclusion Criteria

Alcohol drinkers who consume alcohol on a regular basis
No history of significant substance misuse
At least 12 years of education or GED equivalence

Exclusion Criteria

I have a neurodegenerative disorder.
I have Type 1 Diabetes or my Type 2 Diabetes is not well controlled.
I have epilepsy.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants complete two laboratory sessions with beverages that may or may not contain alcohol

2-4 weeks
2 sessions (in-person)

Follow-up

Participants are monitored for differences in psychomotor skills, working memory, and neural activity under alcohol vs placebo conditions

2 weeks

What Are the Treatments Tested in This Trial?

Trial Overview

The study tests how older adults react to a moderate dose of alcohol compared to a placebo (a non-alcoholic drink). Each participant attends two sessions and completes mental and brain activity tests after drinking either beverage.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Alcohol ConditionExperimental Treatment1 Intervention
Group II: Non-Alcohol SessionPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Florida

Lead Sponsor

Trials
1,428
Recruited
987,000+