147 Participants NeededMy employer runs this trial

Pecan Snacking for Prediabetes

KP
SM
Overseen ByStacey Meily
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether replacing snacks high in saturated fats and added sugars with pecans can help people with prediabetes manage blood sugar and heart health. Participants will either consume 1.5 ounces of pecans daily or maintain their usual diet for 16 weeks. This study suits individuals with prediabetes who enjoy snacks high in saturated fats or added sugars and do not regularly eat nuts. As an unphased trial, it provides a unique opportunity to contribute to research that could enhance dietary recommendations for managing prediabetes.

Do I have to stop taking my current medications for the trial?

If you are taking medications that lower blood pressure, cholesterol, or blood sugar, or certain supplements, you must stop them to participate in the trial. If you are unwilling to stop these, you cannot join the study.

Is there any evidence suggesting that pecan snacking is safe for individuals with prediabetes?

Research has shown that pecans are generally safe for most people. One study found that eating pecans can improve the body's ability to manage sugar, aiding in blood sugar control. Participants who consumed pecans also showed better insulin levels. Another study indicated that pecans did not harm heart health and even reduced certain heart disease risks.

These findings suggest that pecans are well-tolerated and may be beneficial, particularly for those with prediabetes. However, with any dietary change, individuals should monitor their body's response and consult a healthcare provider if concerns arise.12345

Why are researchers excited about this trial?

Unlike traditional treatments for prediabetes, which often involve medication or significant lifestyle changes, pecan snacking offers a natural and simple dietary adjustment. Researchers are excited about this approach because pecans are rich in healthy fats, fiber, and antioxidants, which might help regulate blood sugar levels without major disruptions to daily life. Additionally, replacing snacks high in saturated fats and sugars with pecans could provide multiple health benefits beyond blood sugar control, making it an appealing option for those looking for a more holistic health improvement.

What evidence suggests that pecan snacking might be an effective treatment for prediabetes?

This trial will compare pecan snacking with a usual diet for individuals with prediabetes. Studies have shown that eating pecans can help the body use insulin more effectively, thereby lowering blood sugar levels. Research suggests that replacing usual snacks with pecans may reduce insulin resistance, a condition where the body doesn't respond well to insulin. This is particularly beneficial for people with prediabetes who are at risk of developing type 2 diabetes. Additionally, pecans have been found to improve heart health by lowering bad cholesterol and increasing good cholesterol. Overall, pecans may aid in better blood sugar control and heart health.12678

Are You a Good Fit for This Trial?

This trial is for adults aged 25-65 who have prediabetes, are overweight or obese (BMI 25-40), usually eat snacks high in saturated fat or added sugars, and don't regularly eat many nuts.

Inclusion Criteria

Prediabetes assessed by an HbA1c of 5.7-6.4% at screening
BMI 25-40 kg/m2 at screening
Low habitual nut consumption (<3.5 oz-eq/week) assessed at the telephone screening
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Exclusion Criteria

Participation in another clinical trial within 60 days of baseline
Does not speak and/or understand English
Weight <110 lb
See 25 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are randomized to either replace current snacks with pecans or continue their habitual diet for 16 weeks

16 weeks
2 visits (in-person) at baseline and 16 weeks

Follow-up

Participants are monitored for changes in blood sugar, heart health, and diet quality after the treatment period

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Pecan Snacking

Trial Overview

The study compares two groups: one replaces their usual unhealthy snacks with about 1.5 oz of pecans daily for 16 weeks; the other continues their normal diet. The effects on blood sugar, heart health, and diet quality will be measured.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Pecan snacking groupExperimental Treatment1 Intervention
Group II: Usual dietActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Penn State University

Lead Sponsor

Trials
380
Recruited
131,000+

American Pecan Promotion Board

Collaborator

Trials
1
Recruited
60+

Citations

Pecan Intake Improves Lipoprotein Particle Concentrations ...

Our results showed pecan intake reduced insulin resistance assessed by the LP-IR. ... Replacement of usual snacks with pecans may reduce insulin resistance ...

Eating Pecans had Significant Effect on Biomarkers of ...

Pecan-rich diet significantly improved insulin sensitivity in adults who are overweight or obese. A new study published in Nutrients shows that eating just ...

Do Pecans Lower Blood Sugar? What the Evidence Actually ...

What the Evidence Actually Shows Some trials show lower postprandial glucose when pecans replace refined carbs, others find neutral fasting ...

Cardiometabolic Effects of Pecans as a Snack

Exploratory outcomes included early markers of insulin resistance (i.e. ... Resistance Score were also improved with pecan intake compared to the usual diet group ...

Are Pecans Good for Diabetics

Studies have shown that eating a serving (~1.5oz) of pecans a day can improve serum insulin, insulin resistance, and beta cell function in at-risk adults.

Cardiometabolic Effects of Pecan Snacking in Prediabetes

Participants may experience improved blood sugar control and heart health. Those in the pecan group will receive free pecans for 16 weeks and may learn ...

New Findings Highlight Two Decades of Evidence ...

Findings on pecans' effects on blood sugar and diabetes-related outcomes are mixed, and more research is needed to clarify their role in ...

Are Pecans Good for Diabetics?

The health benefits of pecans are off the charts, making them great for snacking as a diabetic. They contain low carbohydrates, high fiber, healthy fats, and ...