Shockwave Therapy for Erectile Dysfunction
(REVIVE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will investigate whether low-intensity extracorporeal shockwave therapy (LiESWT) can help men recover erectile function after nerve-sparing prostate cancer surgery. Erectile dysfunction is common after this surgery, and current rehabilitation treatments mainly help manage symptoms rather than directly promoting recovery of the affected penile tissues. LiESWT is a non-invasive treatment that uses low-intensity shockwaves and may help improve blood flow and tissue recovery.
The study will include 80 men undergoing nerve-sparing radical prostatectomy. Participants will be randomly assigned to receive either standard penile rehabilitation alone or standard rehabilitation plus eight LiESWT treatments. Erectile function, urinary function, pain, and potential side effects will be assessed throughout the 36-week study period. The main goal is to determine whether adding LiESWT increases the number of men who recover normal erectile function 24 weeks after surgery. The findings may help improve penile rehabilitation and sexual health outcomes for men recovering from prostate cancer surgery.
Are You a Good Fit for This Trial?
This trial is for men who have had nerve-sparing prostate cancer surgery and are experiencing erectile dysfunction. Participants should be able to take part in standard penile rehabilitation after their surgery.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Low-Intensity Extracorporeal Shockwave Therapy
Trial Overview
The study compares standard penile rehabilitation alone versus the same rehab plus eight sessions of low-intensity shockwave therapy (LiESWT). Men are randomly assigned to one group or the other, and results are tracked over 36 weeks.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants will receive standard postoperative penile rehabilitation in combination with LiESWT. LiESWT will be administered in eight treatment sessions during postoperative weeks 3-4 and 10-11, with two sessions per week, 2-3 days apart. Each approximately 15-minute session will deliver 3,000 shockwave impulses at 5 Hz and an energy flux density of 0.09 mJ/mm² to six anatomical penile treatment sites. Standard penile rehabilitation will be prescribed at the discretion of the treating physician.
Participants will receive standard postoperative penile rehabilitation as prescribed by the treating physician, without LiESWT.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Manitoba
Lead Sponsor
Motorcycle Ride for Dad
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.