Pelvic Floor Physical Therapy for Endometriosis

AL
AS
Overseen ByAnastasia Sizov, MD
Age: 18 - 65
Sex: Female
Trial Phase: Academic
Sponsor: University of Alberta
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Endometriosis is a chronic inflammatory condition where there is abnormal tissue growing in the pelvis or other places in the body that resembles the lining of the uterus (endometrium), and is a common cause of long lasting pelvic pain. Surgery is sometimes done for endometriosis to help people with pain, however it is common for people to have some pain after surgery that doesn't go away. This may be related to other painful things like muscle pain in the pelvis, bowel or bladder issues, or mental health conditions.

Researchers would like to know if doing pelvic floor physiotherapy before surgery for endometriosis will help people with long lasting pain after surgery.

Participants in the study will be randomly put into one of two groups: the intervention group, who will receive two to three structured in-person pelvic floor physiotherapy sessions prior to surgery ("prehabilitation"), in addition to usual surgical care, or the control group, who will receive usual surgical care, and may still access physiotherapy outside of the study if they want to. All participants will complete questionnaires before surgery, after completing prehabilitation or immediately before surgery if they are part of the control group, approximately 6 weeks after surgery, 6 months after surgery, and 12 months after surgery. The questionnaires ask about endometriosis-related pain, quality of life, bladder and bowel symptoms, and mental well-being.

Who Is on the Research Team?

AL

Alicia Long, MD, MSc, FRCSC

Principal Investigator

University of Alberta

Are You a Good Fit for This Trial?

This trial is for people with endometriosis who are scheduled to have surgery for pelvic pain. Participants should be able to attend in-person physiotherapy sessions before their operation.

Inclusion Criteria

I am scheduled for surgery to treat endometriosis and preserve fertility or for a hysterectomy.
I have had pelvic pain for more than 6 months.
I have been diagnosed with endometriosis.

Exclusion Criteria

I am having gynecologic surgery and do not have pelvic pain.
Post-menopausal
I am having or may have open abdominal surgery (laparotomy).
See 6 more

What Are the Treatments Tested in This Trial?

Interventions

  • Structured pre-operative pelvic floor physiotherapy program (prehabilitation)

Trial Overview

The study compares two groups: one gets two or three pelvic floor physical therapy sessions before surgery (prehabilitation) plus usual care, and the other receives only usual surgical care. Group assignment is random.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Intervention GroupExperimental Treatment1 Intervention
Group II: Control GroupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Alberta

Lead Sponsor

Trials
957
Recruited
437,000+

Women and Children's Health Research Institute, Canada

Collaborator

Trials
18
Recruited
24,800+