COG+OT Telerehabilitation for Subjective Cognitive Complaints

(CogSCC Trial)

MW
PF
Overseen ByPatricia Finetto, OTR/L
Age: 18+
Sex: Male
Trial Phase: Academic
Sponsor: Medical University of South Carolina
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to assist individuals with memory or thinking concerns through a new online program called COG+OT Telerehabilitation, which combines cognitive and occupational therapy. It targets adults who notice a decline in their thinking or memory, including those with Ehlers-Danlos Syndrome, a condition affecting connective tissues. Participants will use a smartphone or computer to engage in a 6-week virtual therapy to determine if it improves their mental functions. This trial suits those who can use a smartphone and have experienced noticeable changes in their cognitive abilities. As an unphased trial, it provides a unique opportunity to explore innovative therapies that could enhance cognitive health.

What prior data suggests that this telerehabilitation intervention is safe for adults with subjective cognitive complaints?

Research has shown that COG+OT telerehabilitation is generally easy for people to handle. A study on similar programs found these treatments both doable and acceptable for participants, meaning most people can complete the treatment without major issues. Although the study didn't focus on serious side effects, it indicated that people felt comfortable with the method.

While specific data on side effects is lacking, the nature of the treatment suggests it is likely safe. COG+OT combines cognitive and occupational therapy techniques, which are non-invasive and typically safe. Overall, evidence suggests that participants tolerate this treatment well.12345

Why are researchers excited about this trial?

Researchers are excited about COG+OT Telerehabilitation because it offers a novel way to address subjective cognitive complaints through remote delivery, making it accessible to more people, especially those who may have mobility issues or live in remote areas. Unlike traditional cognitive therapies that often require in-person sessions, this method leverages technology to provide cognitive and occupational therapy directly to patients at home. This approach not only aims to improve cognitive function but also enhances day-to-day living skills, which can be particularly beneficial for older adults and individuals with Ehlers-Danlos Syndrome. The convenience and comprehensive nature of this telerehabilitation could revolutionize how cognitive complaints are managed, offering a more flexible and potentially equally effective alternative to conventional treatments.

What evidence suggests that COG+OT Telerehabilitation is effective for subjective cognitive complaints?

Research has shown that telerehabilitation programs like COG+OT can improve thinking skills more effectively than regular care. For example, studies have found that this therapy enhances overall brain function, language, and memory. In this trial, participants will undergo the 6-week COG+OT telerehabilitation intervention. Previous trials demonstrated that COG+OT is practical and well-liked by users, particularly those recovering from a stroke. Additionally, remote cognitive and occupational therapy has helped stroke survivors enhance their thinking skills, suggesting it could also benefit others with similar issues. These findings support its potential effectiveness for individuals with memory or thinking concerns and conditions like Ehlers-Danlos Syndrome.34678

Who Is on the Research Team?

MW

Michelle Woodbury, PhD, OTR/L

Principal Investigator

Medical University of South Carolina

Are You a Good Fit for This Trial?

This trial is for adults who feel they have problems with memory or thinking, including older adults and those diagnosed with Ehlers-Danlos Syndrome. Participants should be able to take part in online sessions and complete assessments before and after the program.

Inclusion Criteria

Endorsement of subjective cognitive complaints with a score ≥4 on the Healthy Brain 9 (HB9)
Access to a device capable of supporting a telerehabilitation visit, such as a phone, tablet, or laptop, and a reliable Wi-Fi or cellular internet connection
Access to and ability to use a smartphone compatible with the NeuroUX platform
See 3 more

Exclusion Criteria

I am unable to participate in study procedures as judged by the study team.
Diagnosis of dementia or mild cognitive impairment
Significant or unstable conditions or treatments for medical conditions that may impact cognition, such as traumatic brain injury or brain tumor

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a 6-week COG+OT telerehabilitation intervention combining cognitive rehabilitation and occupational therapy strategies

6 weeks

Follow-up

Participants are monitored for changes in cognitive function and adherence post-treatment

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • COG+OT Telerehabilitation

Trial Overview

The study tests a 6-week online (telerehabilitation) program that combines cognitive training and occupational therapy to help improve daily thinking skills. All participants receive this intervention, with progress measured before and after treatment.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Older Adults With Subjective Cognitive ComplaintsExperimental Treatment1 Intervention
Group II: Adults With Ehlers-Danlos Syndrome and Subjective Cognitive ComplaintsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Medical University of South Carolina

Lead Sponsor

Trials
994
Recruited
7,408,000+

Citations

A systematic review of cognitive telerehabilitation in patients ...

Telerehabilitation has been shown to be more effective than usual care in improving global cognitive function, and its effectiveness is not ...

Functional Cognitive Rehabilitation as a Primer to Activity ...

This pilot trial evaluated the feasibility and acceptability of a novel stroke telerehabilitation program—COG + OT—that delivers brief, functionally oriented ...

Cognitive telerehabilitation: an expert consensus paper on ...

The aim of this consensus paper is to investigate the current evidence on the use and effectiveness of TR in the cognitive field, trying to also suggest some ...

TELE-REHAB

BASIC DESCRIPTION: Provides a telephone screening for older adults with mild cognitive impairment and / or significant memory complaints. MND-Prism App (EN).

Neurocognitive Effects of an Online Brain Health Program ...

Abstract: Introduction: Adopting healthy lifestyle behaviors has the potential to slow cognitive decline in older adults by reducing risks ...

COG+OT Telerehabilitation for Adults With Subjective ...

COG+OT is a personalized telerehabilitation program that combines cognitive rehabilitation and occupational therapy. Cognitive rehabilitation sessions focus on ...

Cognitive Tele-Enhancement in Healthy Older Adults and ...

This literature review highlights the importance of applying preventive cognitive interventions to subjects with initial subjective memory complaints.

The Effects of Exergame Telerehabilitation in Persons with ...

The Effects of Exergame Telerehabilitation in Persons with Subjective Cognitive Decline - NIH