Neuronal Mechanisms for Epilepsy
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to examine how memories of past experiences are used to guide behavior in novel situations through the cognitive process of abstraction. This project examines how abstract representations are learned, whether and how they support generalization to novel situations, and whether and how they support analogical reasoning.
Who Is on the Research Team?
Adam Mamelak, MD
Principal Investigator
Cedars-Sinai Medical Center
Ueli Rutishauser, PhD
Principal Investigator
Cedars-Sinai Medical Center
Are You a Good Fit for This Trial?
This trial is for adults (18 or older) with hard-to-treat epilepsy who are already having invasive brain monitoring. Participants must have an IQ above 70 and be able to understand and perform simple tasks using a response pad.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo behavioral testing and neuronal recordings while conducting cognitive tests during their hospital stay
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Trial Overview
Researchers are studying how people with epilepsy learn and use abstract ideas by recording brain activity during behavioral tasks, using special electrodes, a response pad, and sometimes mild electrical stimulation.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Behavioral testing and neuronal recordings
Find a Clinic Near You
Who Is Running the Clinical Trial?
Cedars-Sinai Medical Center
Lead Sponsor
University of California, Los Angeles
Collaborator
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator
University of California, Davis
Collaborator
Barrow Neurological Institute
Collaborator
Columbia University
Collaborator
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