Whole Body Vibration for Spinal Degeneration

CV
AS
Overseen ByAlok Shah, MS
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Milwaukee VA Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to understand how whole body vibration (WBV), similar to what military personnel experience, affects the spine over time. It will explore the impact of past and current WBV on spinal health and pain, with a focus on how hydration levels, including water intake, alter spine response. The study involves different groups: some examine long-term effects, others immediate changes, and some assess hydration's role in spine health. Veterans who have experienced WBV in military or civilian jobs, can sit upright for an hour, and are ambulatory might be suitable participants. As an unphased study, this trial offers a unique opportunity to contribute to valuable research that could enhance understanding and care of spinal health.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that whole body vibration is safe for spinal health?

Research shows that whole body vibration (WBV) can negatively affect the spine, especially with long-term exposure. Studies have found that people exposed to WBV for several years may face a higher risk of spinal issues, such as low back pain and early wear and tear of spinal discs. Constant shaking can stress the spine over time.

In this trial, researchers are carefully monitoring the safety of WBV. Advanced MRI scans are being used to observe how the spine reacts to WBV, both in the short term and over longer periods. One focus is hydration, which refers to water intake. The trial examines whether staying hydrated can help maintain spinal health when exposed to WBV.

While WBV is known to cause some spine issues, this trial aims to find safer ways to manage or reduce those effects. It is important to note that the trial does not test a new medication or treatment but seeks to understand how WBV affects the spine.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how whole body vibration (WBV) affects spinal health in ways that current treatments don't. Unlike traditional therapies that mainly focus on managing pain or improving mobility, this study investigates the potential for WBV to influence the spine's structure and fluid dynamics directly. One unique aspect of this trial is its exploration of how hydration levels impact the spine's response to vibration, which could lead to new strategies for preventing or treating spinal degeneration. This approach could open up new pathways for rehabilitation and prevention that are more individualized and potentially more effective over time.

What evidence suggests that this trial's treatments could be effective for spinal degeneration?

Research has shown that whole-body vibration (WBV) can affect the spine, particularly the soft discs between the spine's bones. Some studies suggest that over time, WBV might cause these discs to wear down, leading to back pain. However, other research indicates that WBV therapy can sometimes help reduce pain and improve movement in people with low back pain. This trial includes separate arms to explore different aspects of WBV's effects. One arm investigates the longitudinal effects of current or prior WBV on lumbar spine health. Another arm examines how WBV acutely affects lumbar disc fluid flow. Additionally, the study explores how staying hydrated might influence the spine's response to WBV. By keeping the spine's cushioning well-hydrated, it might better handle vibration, potentially benefiting people whose jobs expose them to WBV.12678

Who Is on the Research Team?

BD

Brian D Stemper, PhD

Principal Investigator

Milwaukee VA Medical Center

Are You a Good Fit for This Trial?

This trial is for U.S. military veterans aged 20-45 who can speak English, have a BMI under 30, can sit upright for an hour, drive to Deerfield, IL, and are able to walk on their own.

Inclusion Criteria

I am a veteran aged 20-45, with a BMI under 30, can sit upright for an hour, drive to Deerfield, IL, and can walk.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Initial MRI scans and questionnaires to assess baseline spine health and whole body vibration exposure history

1-2 weeks
1 visit (in-person)

Acute WBV Exposure

Participants undergo experimental whole body vibration exposure and pre/post MRI scans to assess acute changes

1 day
1 visit (in-person)

Longitudinal Monitoring

Annual MRI scans and questionnaires to track progression of spine changes over three years

3 years
3 visits (in-person, annually)

Follow-up

Participants are monitored for safety and effectiveness after the main study phases

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Water

Trial Overview

The study uses advanced MRI techniques to examine the spine's structure and physiology after exposure to whole body vibration (WBV), both from past military service and current civilian jobs like truck driving.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Group I: Effect of hydration on lumbar spine response to whole body vibrationExperimental Treatment1 Intervention
Group II: Longitudinal effects of current or prior whole body vibration.Active Control1 Intervention
Group III: Determine how lumbar disc fluid flow is acutely affected by whole body vibratiActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Milwaukee VA Medical Center

Lead Sponsor

Trials
4
Recruited
390+

Medical College of Wisconsin

Collaborator

Trials
645
Recruited
1,180,000+

Indiana University

Collaborator

Trials
1,063
Recruited
1,182,000+

VA Office of Research and Development

Collaborator

Trials
1,691
Recruited
3,759,000+

Naval Aeromedical Research Unit, Dayton

Collaborator

Trials
1
Recruited
320+

Citations

Occupational Exposure to Whole Body Vibration Among ...

This study will investigate acute and chronic effects of occupational whole-body vibration on the health of lumbar spine endplates and ...

Whole Body Vibration for Spinal Degeneration

This N/A medical study run by Milwaukee VA Medical Center needs participants to evaluate whether Water will have tolerable side effects ...

Whole-Body Vibration to Treat Low Back Pain: Fact or Fad?

The purpose of this systematic review was to evaluate the current evidence base for whole-body vibration as a treatment for low back pain (LBP).

Long-term whole-body vibration induces degeneration of ...

Conclusion: The present study revealed significant damage effects of Whole body vibration on intervertebral disc and facet joint in a bipedal ...

Vibration therapy to improve pain and function in patients with ...

The results showed that both whole-body vibration therapy and local vibration therapy improved patients' low back pain. In terms of improvement ...

Deleterious effects of whole‐body vibration on the spine - PMC

Such studies have found that greater duration of exposure (over 5 years) to WBV is associated with increased risk for spinal pathologies and that the lumbar ...

Whole Body Vibration - an overview

With the knowledge that whole-body vibration is a real medical problem, when we look at the possible effects: low back pain, early degeneration of the spinal ...

Long-term whole-body vibration induces degeneration ... - PMC

The present study revealed significant damage effects of Whole body vibration on intervertebral disc and facet joint in a bipedal mouse model.