5000 Participants Needed

Biomarkers for Diabetic Foot Ulcers

Recruiting at 7 trial locations
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Michigan
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to identify specific biomarkers that can predict the likelihood of healing in diabetic foot ulcers (open sores on the foot). Understanding these markers may help doctors make better treatment decisions and improve future therapies. People with diabetes who have an open wound on their foot and are willing to provide samples and data might be suitable for this study. As an unphased study, this trial offers participants the chance to contribute to groundbreaking research that could significantly enhance treatment strategies for diabetic foot ulcers.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to identify biomarkers for active diabetic foot ulcers, which could revolutionize how we approach treatment. Unlike current methods that primarily focus on wound care and infection control, uncovering specific biomarkers could lead to earlier detection and personalized treatment plans. This approach has the potential to improve healing rates and prevent serious complications by tailoring interventions to the unique biological profile of each patient.

Are You a Good Fit for This Trial?

Inclusion Criteria

You must provide a signed and dated consent form.
You have been clinically diagnosed with diabetes, or meet the American Diabetes Association criteria.
You have an open foot ulcer extending from the malleolus down, including post-surgical wounds which are left to heal by secondary intention
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Biomarker Testing

Participants undergo biomarker testing to identify diabetic foot ulcers with a higher potential for healing

52 weeks
Visits every other week for one month, then monthly

Follow-up

Participants are monitored for wound healing and recurrence, with assessments at weeks 52 and 78

26 weeks
Phone call or video visit at weeks 52 and 78

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Michigan

Lead Sponsor

Trials
1,891
Recruited
6,458,000+

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

Trials
2,513
Recruited
4,366,000+
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