Maternal Mental Health Access for Postpartum Depression
(MaMa Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests different methods of delivering a mental health program for women experiencing postpartum depression. The goal is to identify the most effective way to offer support using remote and on-demand tools, such as discussion boards and video conferences, integrated with regular maternal care. Participants will help researchers assess the effectiveness of these methods in managing symptoms. The trial seeks pregnant or postpartum women who have experienced depression, anxiety, or major life changes and are attending specific health clinics. As an unphased trial, this study provides a unique opportunity to contribute to innovative mental health solutions and enhance support for postpartum women.
Will I have to stop taking my current medications?
Yes, if you are currently taking any medications for a mental health condition, you cannot participate in this trial.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that digital mental health tools, like those in this trial, are generally safe and easy to use. For example, the FDA has approved the MamaLift Plus app, which helps manage postpartum depression, indicating it meets safety standards for treating mild to moderate postpartum depression.
For the On-Demand and Video Conference options, studies indicate that these tools are well-received and easy to use. Women who used these digital tools for postpartum depression reported positive experiences and found them practical for regular use. This is important because when a treatment is easy to use, adherence increases, which can improve mental health.
Overall, while specific data on side effects for every digital tool might not exist, existing evidence supports their general safety. Many users find them a convenient way to manage mental health, making them a promising option for those dealing with postpartum depression.12345Why are researchers excited about this trial?
Researchers are excited about these treatments for postpartum depression because they offer flexible, on-demand mental health support tailored to new mothers. Unlike traditional therapy, which usually requires scheduled appointments, these options allow mothers to access resources at their convenience, either through an online platform alone or with added support from discussion boards or video conferences. This adaptability not only makes mental health care more accessible but also integrates seamlessly into the busy lives of new mothers, potentially improving engagement and outcomes.
What evidence suggests that this trial's treatments could be effective for postpartum depression?
Research shows that about 10% of women experience postpartum depression (PPD) after childbirth. Studies have found that Mindfulness-Based Cognitive Therapy (MBCT) can help prevent PPD. In this trial, participants will access different digital versions of MBCT. One option includes On-Demand (OD) access alone or with a facilitated discussion board (DB). Another option combines On-Demand (OD) access with Video Conference (VC) support. These digital methods, which have shown promise in reducing symptoms of depression during and after pregnancy, are included in maternal care to assist women at risk. Telehealth, such as video calls, can effectively manage PPD by providing easy access to mental health support.12678
Who Is on the Research Team?
Gwen Latendresse
Principal Investigator
University of Utah
Are You a Good Fit for This Trial?
This trial is for pregnant or postpartum women (up to 1 year after birth) who are at least 18 years old, speak English or Spanish, and attend certain clinics. They must be at risk for postpartum depression but not have severe mental health conditions like psychosis or bipolar disorder, substance use disorders, severe anxiety, suicidality, or be on current mental health medications.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants engage in an 8-week remote-access MBCT or multimedia on-demand program, with options for facilitated discussion boards or synchronous videoconference sessions
Follow-up
Participants are monitored for changes in depressive symptoms using the EPDS at multiple timepoints post-intervention
What Are the Treatments Tested in This Trial?
Interventions
- Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention
- On-Demand + Discussion board (DB)
- On Demand (OD) + Video Conference (VC)
Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention is already approved in United States for the following indications:
- Prevention of postpartum depression
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Utah
Lead Sponsor
National Institute of Nursing Research (NINR)
Collaborator