MoodTriggers App for Depression

Not yet recruiting at 1 trial location
NC
Overseen ByNicholas C Jacobson, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Dartmouth-Hitchcock Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if smartphone data can predict the return of depression symptoms. Participants will either use a special app called the MoodTriggers Application, which collects data from phone sensors, or continue with regular care. Researchers hope this could lead to earlier interventions for more effective depression management. The trial is open to adults treated for depression who are currently symptom-free and can use a smartphone. As an unphased trial, participants have the opportunity to contribute to innovative research that could transform depression management.

Do I need to stop my current medications for the MoodTriggers App trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on monitoring depression symptoms through smartphone data, so you may not need to change your medication routine.

What prior data suggests that the MoodTriggers App is safe for use in monitoring depression symptoms?

In studies with similar apps, researchers found these tools generally safe for users. The MoodTriggers app collects data from phones to help understand mood changes. Research on digital mental health tools has shown they are usually well-tolerated, meaning people can use them without major problems.

Some studies suggest these apps can safely help track mental health symptoms. So far, no major reports of negative side effects have emerged. This suggests that using the MoodTriggers app is likely safe, based on knowledge of similar apps.12345

Why are researchers excited about this trial?

Researchers are excited about the MoodTriggers App for depression because it offers a unique approach to managing mental health. Unlike traditional treatments like medication or therapy, this app leverages smartphone sensors to continuously monitor mood-related data, providing real-time insights. This innovative method could potentially detect early warning signs of depression, allowing for timely interventions. Additionally, its ease of use and accessibility through a smartphone make it a convenient option for many, potentially reaching individuals who might otherwise not seek help.

What evidence suggests that the MoodTriggers App is effective for predicting depression symptoms?

Research has shown that the MoodTriggers App can help lessen symptoms of depression. In this trial, participants may be assigned to use the app, which has reduced depression symptoms compared to non-users. The app analyzes information from the phone to identify factors that might affect mood. Early results suggest it provides personalized advice based on this data, aiding in depression management. Users have rated the app positively, with an average rating of 4 out of 5 stars. Overall, promising evidence indicates that the MoodTriggers App can effectively track and possibly reduce depression symptoms.46789

Who Is on the Research Team?

NC

Nicholas C Jacobson, PhD

Principal Investigator

Dartmouth College

Are You a Good Fit for This Trial?

This trial is for individuals with depression or major depressive disorder. Participants should be comfortable using a smartphone regularly, as the study involves monitoring through a mobile application.

Inclusion Criteria

Have access to and ability to use a smartphone (Android version ≥ 6 or iOS version ≥ 11)
I am 18 years old or older.
I was treated for depression at a Dartmouth Health site and left the program not feeling depressed.

Exclusion Criteria

Identified as high risk due to active suicidality, psychosis, or bipolar disorder
I still feel very depressed after finishing my depression care program.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Sensing System Calibration

Participants download an app on their smartphone to collect data from phone sensors and answer mood questions monthly

6 months
Monthly virtual check-ins

Early Warning System

Randomized phase where participants either use the app or receive usual care, with monthly mood questionnaires

6 months
Monthly virtual check-ins

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • MoodTriggers Application
Trial Overview The study tests if data from smartphones can predict the return of depression symptoms. It aims to develop an app that helps healthcare providers monitor and respond to patients' mental health needs more effectively.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Group I: Phase 1: Sensing System Calibration (N = 120)Experimental Treatment1 Intervention
Group II: Phase 2: Early warning system (n = 100)Active Control1 Intervention
Group III: Phase 2: Usual Care (n = 100)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Dartmouth-Hitchcock Medical Center

Lead Sponsor

Trials
548
Recruited
2,545,000+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials
394
Recruited
404,000+

Citations

Evaluating a mobile app's effects on depression and ...The application was well-received (median app rating = 4/5 stars). The intervention group showed significant reductions in depressive and ...
Using a Smartphone App to Target Current Mental Health ...Mood Triggers was designed to provide personalized feedback on individuals' maintenance factors (i.e., "triggers") of their anxiety and depressive symptoms ...
Passive Sensing of Prediction of Moment-To ...The current study utilized passively collected sensor data collected from a smartphone application to future depressed mood from hour-to-hour.
(PDF) Evaluating a mobile app's effects on depression and ...The application was well-received (median app rating = 4/5 stars). The intervention group showed significant reductions in depressive and ...
Use of smartphone sensor data in detecting and predicting ...This brief review summarised how studies have combined passive data from wearables and smartphones with active self-report data to better ...
Improving the Utility, Safety, and Ethical Use of a Passive ...This study aims to explore how a passive behavioral monitoring platform, Remote Assessment of Disease and Relapse, would meet the needs of people with BD.
Assessing the Efficacy and Safety of a Digital Therapeutic ...This protocol describes a virtual randomized controlled trial designed to evaluate the efficacy and safety of a self-guided, mobile app–based implementation of ...
Nicholas C. Jacobson, PhDHe recently developed an anxiety and depression monitoring application entitled Mood Triggers which helps users to learn the triggers of their anxiety and ...
Can Digital Therapeutics Help Solve the Mental Health Crisis?Jacobson's journey from therapy to technology began in graduate school, where he started developing Mood Triggers, a smartphone app that helps ...
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