Professional Dental Plaque Disruption for Tooth Decay

KA
Overseen ByKhaled Altabtbaei, BDM, PhD
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: University of Alberta
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.

Families with children aged 5-12 years will be recruited from university dental clinics. Participants will be assigned to one of three treatment groups: treatment for the child only, treatment for the child and parents, or treatment for all family members. Researchers will collect oral bacterial samples from family members before and after treatment and will monitor close-contact interactions within the household using wearable proximity-tracking devices.

The study will also collect information about oral health habits, family interactions, and environmental factors that may influence bacterial transmission. By combining bacterial DNA analysis with information about family contact patterns, researchers hope to better understand how oral bacteria are shared within households and whether family-based treatment approaches can reduce bacterial recolonization after dental therapy.

The results of this study may help improve strategies for preventing childhood tooth decay and gum disease by addressing family-level sources of bacterial transmission.

Are You a Good Fit for This Trial?

This trial is for families with children aged 5-12 who are patients at university dental clinics. All family members must be willing to participate in oral health assessments and treatments, as well as provide samples and wear proximity-tracking devices.

Inclusion Criteria

My parent or guardian has been treated for moderate to severe gum disease.
At least one child who has undergone caries treatment and is considered at high risk for disease recurrence
Willingness of all participating household members to provide oral samples and participate in study procedures
See 2 more

Exclusion Criteria

Children living in multiple households or shared-custody arrangements during the study period
Households unable to complete study visits or follow-up procedures
Individuals unwilling or unable to comply with study procedures
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What Are the Treatments Tested in This Trial?

Interventions

  • Professional Dental Plaque Disruption

Trial Overview

The study tests whether treating just the child, the child plus parents, or all family members with professional dental plaque removal can better prevent harmful bacteria from returning after treatment. Family interactions and bacterial spread will also be monitored.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Whole-Family TreatmentExperimental Treatment1 Intervention
Group II: Child-Only TreatmentExperimental Treatment1 Intervention
Group III: Child Plus Parents TreatmentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Alberta

Lead Sponsor

Trials
957
Recruited
437,000+