TEE Techniques for Swallowing Difficulty After Lung Transplant
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether reducing the number of heart images taken during lung transplants can lessen swallowing difficulties afterward. It uses a heart imaging technique called transesophageal echocardiography (TEE), which captures images from inside the body. Participants are divided into two groups: one with limited TEE images and the other with the number determined by the doctor. This trial suits adults who have had single or double lung transplants and do not have specific esophagus issues. As an unphased trial, it offers participants the chance to contribute to innovative research that could enhance post-transplant recovery.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this TEE technique is safe for patients with swallowing difficulty after lung transplant?
Research has shown that transesophageal echocardiography (TEE) is a common procedure during lung transplants. TEE, which involves taking pictures of the heart from inside the body, is generally safe. This study examines whether the number of TEE images, or "clips," affects swallowing difficulties after surgery.
While there is limited direct information on the safety of taking fewer TEE clips, TEE itself is well-known and widely used. Complications are rare, though some patients might experience mild throat discomfort. The study focuses on whether reducing the number of clips can alleviate swallowing issues post-transplant. Overall, TEE is a common practice and is considered safe for most patients.12345Why are researchers excited about this trial?
Researchers are excited about these techniques for managing swallowing difficulties after lung transplants because they explore how varying the number of transesophageal echocardiography (TEE) clips could impact patient outcomes. Unlike traditional approaches where the number of TEE clips is determined entirely by the attending anesthesiologist, this trial examines whether limiting the clips could reduce complications or improve recovery. This investigation could lead to a more standardized and potentially safer protocol for patients experiencing swallowing issues post-transplant.
What evidence suggests that limiting TEE clips is effective for reducing swallowing difficulty after lung transplant?
Research shows that Transesophageal Echocardiography (TEE) is often used during lung transplants to monitor the heart. However, some studies suggest that this procedure might make swallowing difficult afterward. One study found that TEE image quality was affected in some patients who had previous esophageal surgery, indicating possible complications. This trial will compare two approaches: one arm will limit the number of TEE clips taken during the procedure, while the other arm will allow the attending anesthesiologist to determine the number of TEE clips. The current research investigates whether taking fewer images during TEE could reduce the risk of swallowing problems after lung transplants. Although solid data on this idea is not yet available, the study aims to determine if a simpler approach could help.13467
Who Is on the Research Team?
J.Prince Neelankavil, MD
Principal Investigator
University of California, Los Angeles
Are You a Good Fit for This Trial?
This trial is for adult patients undergoing single or double lung transplantation at UCLA. It's not suitable for individuals with conditions like a perforated esophagus, narrowed esophagus, esophageal cancer, or those who have had their esophagus removed. Patients needing a tracheostomy after surgery are also excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo lung transplantation with TEE performed, randomized to either limited or standard number of TEE clips
Postoperative Evaluation
Postoperative speech and swallow evaluation performed by a speech/language therapist
Follow-up
Participants are monitored for dysphagia and other outcomes until discharge from the hospital
What Are the Treatments Tested in This Trial?
Interventions
- Transesophageal Echocardiography (TEE) with limited number of TEE clips
- Transesophageal Echocardiography (TEE) with number of TEE clips per attending anesthesiologist
Transesophageal Echocardiography (TEE) with limited number of TEE clips is already approved in United States, European Union for the following indications:
- Cardiovascular imaging
- Monitoring during surgical procedures
- Cardiovascular imaging
- Monitoring during surgical procedures
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Los Angeles
Lead Sponsor