Mobile Mindfulness for Psychological Distress in Critical Illness

(Lift 3 Trial)

This trial tests a mobile app called Lift, a mindfulness program designed for survivors of serious heart or lung illnesses. Conditions like heart failure or severe COVID often result in ongoing depression, anxiety, and stress. The study compares Lift to another app-based program, the Enlighten Recovery education program, to determine which better improves mental health and quality of life over six months. Individuals hospitalized for a serious heart or lung issue with lasting anxiety or depression may be suitable for this trial. Participants should understand English or Spanish well enough to use the app and complete study tasks. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance mental health support for individuals facing similar health challenges.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.

Research has shown that Lift, a mobile mindfulness app, is safe for users. Studies have found that Lift reduces symptoms of depression and anxiety. No reports of harmful side effects exist. Users found the app easy to use and well-liked overall. This suggests that the app is safe and comfortable for those seeking to manage stress and emotional challenges.¹²³⁴⁵

Unlike traditional treatments for psychological distress in critical illness, which often rely on medications or in-person therapy, Lift mobile mindfulness offers a unique, app-based approach. This mobile mindfulness program can provide immediate access to stress reduction techniques anytime and anywhere, making it highly accessible and convenient. Researchers are excited about this treatment because it not only empowers patients to manage their distress independently but also integrates seamlessly into their daily lives, potentially leading to improved mental health outcomes without the need for additional medication.

Research has shown that the Lift mobile mindfulness program, which participants in this trial may receive, can improve mental health for those recovering from serious illnesses. One study found that Lift reduced depression symptoms and improved quality of life more effectively than an educational program. Another study found that Lift was better at reducing distress than a phone-based mindfulness program or an educational control. These findings suggest that the Lift app could help manage stress, depression, and anxiety for survivors of serious heart and lung conditions. Meanwhile, the Enlighten Recovery education program, another treatment option in this trial, serves as an active comparator to evaluate its effectiveness against Lift.¹²³⁴⁶