3800 Participants NeededMy employer runs this trial

Flo Digital Contraceptive for Birth Control

(FDC Trial)

CA
KB
Overseen ByKeith Boland
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to learn if the Flo Digital Contraceptive (FDC) app can effectively prevent unintended pregnancy in women aged 18 years and older residing in the United States. The main questions it aims to answer are:

What is the rate of unintended pregnancy in women aged 18-35 years using FDC as their sole method of contraception under typical-use conditions, measured using the Pearl Index? What is the cumulative probability of unintended pregnancy over 13 menstrual cycles for all participants, including those with regular and irregular cycles?

Participants will:

Use the Flo Digital Contraceptive app in 'prevent pregnancy' mode as their primary method of contraception for up to 13 menstrual cycles or 18 months, whichever comes first Wear an Apple Watch (Series 8 or later, or Ultra) while sleeping to collect nightly wrist temperature data, which the app uses to detect ovulation Log menstrual cycles, sexual activity, and any use of emergency contraception directly in the Flo app Complete monthly electronic surveys (ePROs) administered by the study team covering pregnancy status, adherence, safety, and experience Complete a baseline demographic survey at enrollment and an exit survey at the end of participation

Who Is on the Research Team?

SM

Shannon Maclaughlan-David, MD, MS

Principal Investigator

Lindus Health

Are You a Good Fit for This Trial?

This trial is for women aged 18 and older in the US who want to use the Flo Digital Contraceptive app as their only birth control method. Participants must be willing to wear an Apple Watch at night, track their cycles and sexual activity in the app, and complete monthly surveys.

Inclusion Criteria

Reside in the United States of America
Possession of an iOS mobile device (version 16 or higher) with internet connectivity
Sufficient English proficiency for correct use of intervention and device
See 8 more

Exclusion Criteria

Any condition or circumstance compromising ability to comply with protocol, safety, or study evaluation as judged by Lead Investigator
≤12 weeks postpartum including terminations >14 weeks or birth >12 weeks postpartum without return of menses
Postabortion with history of cycles outside 21-35 day range or no return of menses
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Enrollment and Baseline

Participants complete a baseline demographic survey and activate the Flo Digital Contraceptive device

1 week
1 visit (virtual)

Treatment

Participants use the Flo Digital Contraceptive app as their primary method of contraception for up to 13 menstrual cycles or 18 months

Up to 18 months
Monthly electronic surveys (ePROs)

Follow-up

Participants complete an exit survey at the end of participation and are monitored for safety and effectiveness

1-2 weeks

What Are the Treatments Tested in This Trial?

Trial Overview

The study tests if the Flo Digital Contraceptive app can effectively prevent pregnancy when used alone. Women will use the app with nightly wrist temperature data from an Apple Watch for up to 13 menstrual cycles or 18 months while logging relevant health info.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Single Arm Device InterventionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Flo Health Inc.

Lead Sponsor

Lindus Health

Industry Sponsor

Trials
12
Recruited
17,000+