H-HOPE for Birth Defects

(H-HOPE Trial)

This trial explores a special program called H-HOPE, designed to assist infants born with congenital defects who require surgery shortly after birth. The goal is to determine if this program improves infant feeding, growth, and development, as well as the mental health of their parents. The trial compares the H-HOPE program, which involves parents learning to interact with and massage their babies, with standard hospital care. Families with infants needing neonatal surgery for congenital defects, who are stable and on minimal respiratory support, may be suitable for this study. As an unphased trial, it offers families the chance to contribute to innovative care strategies that could enhance outcomes for both infants and parents.

The trial information does not specify whether participants need to stop taking their current medications. However, infants must be off all intravenous (IV) pain medications to participate.

Research has shown that the H-HOPE program is generally well-received by both infants and their parents. In past studies, H-HOPE helped infants grow and develop better, without major safety issues. One study found that infants who participated in H-HOPE had better health compared to those who did not. Parents also provided positive feedback about their experience with the program.

Researchers are excited about the H-HOPE intervention for preterm infants because it offers a unique, multisensory approach that empowers parents to actively engage in their baby's development. Unlike standard care options that primarily rely on professional interventions, H-HOPE includes parent-led components like Parents+ and Massage+, teaching parents to interpret and respond to their infant’s cues. This approach not only fosters bonding but also potentially enhances the infant's sensory and neurological development through regular, personalized interaction. By involving parents directly, H-HOPE aims to improve developmental outcomes in a way that is both hands-on and nurturing.

Research has shown that the H-HOPE program, which participants in this trial may receive, offers promising benefits for babies, particularly those born early or at risk. Studies have found that H-HOPE helps babies gain weight and grow better from birth until hospital discharge. It also supports their development and strengthens the bond between mothers and their babies. Parents have reported better experiences, and hospitals have saved money with H-HOPE. While these benefits have been observed in both healthy and at-risk babies, this trial specifically examines its effects on babies with birth defects.¹³⁴⁵⁶