100 Participants NeededMy employer runs this trial

Nurse-Led Therapy for Post-Traumatic Stress Disorder

Recruiting at 1 trial location
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Rush University Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new program, NurseNET, which trains nurses to provide trauma care for people with PTSD. By offering a short-term treatment called Narrative Exposure Therapy (NET), the study aims to determine if nurses can effectively help patients process difficult memories and improve PTSD symptoms. Researchers are interested in whether this nurse-led approach can facilitate access to care and improve health outcomes, such as blood pressure. The trial seeks primary care patients at Rush University Medical Center who have PTSD symptoms and have experienced a serious heart event in the last 90 days. As an unphased trial, this study presents a unique opportunity to contribute to innovative research that could enhance access to trauma care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. However, if you are actively receiving psychotherapy or PTSD treatment, you may not be eligible to participate.

What prior data suggests that the NurseNET program is safe for PTSD treatment?

Research has shown that Narrative Exposure Therapy (NET), the foundation of the NurseNET program, is a well-accepted treatment for post-traumatic stress disorder (PTSD). Studies have demonstrated that NET effectively reduces PTSD symptoms, stress, and anxiety in participants. For instance, one study found that NET helped lower PTSD symptoms and stress in frontline healthcare workers. Another study showed that individuals with severe mental illness and PTSD from repeated trauma also experienced improvements with NET.

These findings suggest that NET, and therefore NurseNET, is generally safe for people with PTSD. No major reports of negative effects from NET have emerged in these studies, indicating that most people tolerate it well. This makes it a promising option for safely treating PTSD symptoms.12345

Why are researchers excited about this trial?

Researchers are excited about NurseNET because it's a fresh approach to treating PTSD by integrating therapy into primary care. Unlike traditional methods that often require specialized mental health professionals and longer sessions, NurseNET empowers primary care nurses to deliver a condensed version of Narrative Exposure Therapy in just four sessions. This innovative task-sharing model not only makes PTSD treatment more accessible but also fits seamlessly into regular healthcare visits, potentially improving patient outcomes by reaching individuals who might otherwise lack access to mental health services.

What evidence suggests that the NurseNET program could be an effective treatment for PTSD?

Research has shown that narrative exposure therapy (NET) effectively reduces symptoms of post-traumatic stress disorder (PTSD). Past studies have demonstrated significant decreases in PTSD symptoms, with improvements observed both immediately after treatment and at follow-up. For instance, one study found a strong reduction in symptoms right after treatment and even more improvement later. NET has successfully helped various groups, including refugees and veterans. In this trial, the NurseNET program aims to expand access to this proven therapy by training nurses to provide it in the experimental arm. By integrating NET into primary care, NurseNET could make PTSD treatment more accessible to those in need.14678

Are You a Good Fit for This Trial?

This trial is for adults who are primary care patients at Rush University Medical Center, have had a serious heart event in the past 90 days (like a heart attack or stroke), and show signs of PTSD after experiencing trauma.

Inclusion Criteria

I have not had a life-threatening heart or stroke event in the past 90 days.
* o PTSD + trauma exposure (PCL-5 score ≥28, plus trauma endorsed on LEC-5/CAPS)
* Primary care patient at Rush University Medical Center

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the NurseNET program, consisting of 4 to 6 sessions of Narrative Exposure Therapy delivered by trained nurses

4-6 weeks
4-6 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, with assessments at multiple time points

12 months
Assessments at 3, 6, and 12 months

What Are the Treatments Tested in This Trial?

Interventions

  • NurseNET

Trial Overview

The study compares usual referrals to PTSD treatment with NurseNET, where trained nurses provide short-term trauma therapy (Narrative Exposure Therapy) through 4-6 sessions in a primary care setting. The goal is to see if nurse-led therapy helps reduce PTSD symptoms.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: NurseNETExperimental Treatment1 Intervention
Group II: Minimally-Enhanced Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Rush University Medical Center

Lead Sponsor

Trials
448
Recruited
247,000+

Citations

The effectiveness of narrative exposure therapy - PMC - NIH

Narrative exposure therapy is effective in post-traumatic stress disorder symptom reduction at post-treatment (g = 1.18) and follow-up (g = 1.37).

Online narrative therapy intervention improves post-traumatic ...

Regarding the dichotomous PTSD, anxiety, and depression outcomes, there was a statistically significant decrease in the number of positive cases of PTSD (p = ...

NCT07430657 | Nurse-Led PTSD Treatment in Primary Care

This study is testing a new program called NurseNET. The goal of NurseNET is to train nurses to provide a proven, short-term trauma treatment called Narrative ...

Effectiveness of Narrative Exposure Therapy for Treatment ...

Narrative exposure therapy (NET) has shown promising outcomes for treating posttraumatic stress disorder (PTSD) in refugees and veterans.

Investigating the Efficacy and Experiences With Narrative ...

Narrative exposure therapy (NET) is an effective trauma therapy. It is unknown whether NET is effective and tolerable in these patients ...

Narrative exposure therapy for posttraumatic stress disorder ...

The primary aim is to evaluate NET in SMI patients with comorbid PTSD associated with repeated interpersonal trauma to get insight into whether ...

Nurse-Led Therapy for Post-Traumatic Stress Disorder

This study is testing a new program called NurseNET. The goal of NurseNET is to train nurses to provide a proven, short-term trauma treatment ...

Practical guidelines for online Narrative Exposure Therapy ...

This paper focuses on practical guidelines using online Narrative Exposure Therapy (e-NET). It aims to be an addition to the general manual of NET.