Transanal Irrigation for Anterior Resection Syndrome

This trial explores whether transanal irrigation (TAI), a method to manage bowel movements, can improve quality of life for individuals with low anterior resection syndrome (LARS) after bowel surgery. The study examines if TAI aids in bowel control and reduces urgent bathroom trips within the first year post-surgery. Participants include patients who have undergone specific bowel surgery and are preparing for an ileostomy closure within 12 months. As an unphased study, this trial provides patients the chance to contribute to research that may enhance post-surgical recovery and quality of life.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that transanal irrigation (TAI) is generally easy for patients to use. Studies have found that TAI can help people with low anterior resection syndrome (LARS) feel better over the long term. In these studies, patients reported high satisfaction and experienced significant symptom relief for several years. This suggests that TAI is safe and might improve quality of life by making bowel movements more predictable and reducing urgency. Although large clinical trials are not yet available, current evidence supports its safety and effectiveness for managing LARS symptoms.¹²³⁴⁵

Researchers are excited about transanal irrigation (TAI) for anterior resection syndrome because it offers a new approach that goes beyond the usual conservative management options. Unlike standard treatments that often involve dietary changes, medications, and pelvic floor exercises, TAI uses a specialized irrigation kit to directly flush out the lower bowel. This method can provide more immediate and controlled relief from symptoms. Additionally, the integration of the LARS app, which supports patients in managing their condition, enhances the potential for personalized and effective treatment.

Research has shown that transanal irrigation (TAI), which participants in the TAI-intervention arm of this trial will receive, can greatly help people with low anterior resection syndrome (LARS). One study found that patients using TAI had much lower LARS scores upon hospital discharge, indicating significant symptom improvement. Another study identified TAI as one of the most effective treatments for severe LARS, with noticeable short-term improvements. Patients have reported better control over bowel movements and an improved quality of life. Overall, TAI appears to be a promising method for managing bowel function after surgery.²³⁴⁶⁷