540 Participants NeededMy employer runs this trial

Artificial Intelligence for Colonic Polyps

(CADx-Prosp Trial)

Recruiting at 1 trial location
Dv
Overseen ByDaniel von Renteln, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Computer-aided image-enhanced endoscopy can predict the nature of colorectal polyps with over 90% accuracy. This technology uses artificial intelligence (AI) to analyze video recordings of polyps, learning to make diagnoses in real-time. This means that doctors can get immediate predictions about small polyps during the procedure, reducing the need for separate pathology exams and saving costs, ultimately improving patient care.

Human and AI interactions are complex and a framework to reap synergistic effects CADx systems when used by humans to harness optimal performance needs to be established. AI solutions in medicine are usually developed to be used as assistive devices, however, then they rely on humans to correct AI errors. Optical polyp diagnosis is a complex task. Non experts usually achieve diagnostic accuracy in 70-80%. CADx systems have a similar diagnostic accuracy when used autonomously. Clinical evaluation of CADx systems showed that CADx assisted OD performs equally to the operator performance when using non CADx assisted OD. To harness a benefit of clinical CADx implementation we would have to find a way that synergies between human and CADx come into play to eliminate cases in which CADx assisted and/ or human OD results in low diagnostic accuracy and also addresses the problem of serrated polyp recognition.

Who Is on the Research Team?

Dv

Daniel von Renteln, MD

Principal Investigator

University of Montreal Medical Center (CHUM)

Are You a Good Fit for This Trial?

This trial is for people who need a full colonoscopy. There are no other major restrictions listed.

Inclusion Criteria

I need a full colonoscopy.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Endoscopists perform optical diagnosis using both standard and image-enhanced endoscopy, followed by CADx-assisted diagnosis

up to 100 weeks

Follow-up

Participants are monitored for diagnostic accuracy and cost-effectiveness of optical diagnosis methods

up to 100 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • CADx (AI) system

Trial Overview

The study compares two ways to diagnose colon polyps during endoscopy: one uses an AI system (CADx) alone, and the other has doctors use the AI as an assistant. The goal is to see which method gives more accurate results in real-time.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: All participantsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Centre hospitalier de l'Université de Montréal (CHUM)

Lead Sponsor

Trials
389
Recruited
143,000+

Roupen Djinbachian, MD

Collaborator

Trials
1
Recruited
540+

Mahsa Taghiakbari, MD PHD

Collaborator

Trials
1
Recruited
540+