500 Participants NeededMy employer runs this trial

RAMP Program for Chronic Pain

(RAMP Trial)

DB
LC
Overseen ByLee Cross, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Minneapolis Veterans Affairs Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help Veterans manage chronic pain by exploring the connection between the mind and body. Participants will learn techniques to better control their pain through remote sessions. The trial includes two groups: one participates in the RAMP mind-body program (a therapeutic approach), and the other continues with their usual care. Those who have experienced chronic pain regularly over the past three months and live in rural areas might be a good fit. Participants need internet access and must be willing to engage in online sessions.

As an unphased trial, this study offers a unique opportunity to explore innovative pain management techniques that could enhance participants' quality of life.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the RAMP Program is safe for managing chronic pain?

Research has shown that the RAMP Program, which uses mind-body techniques to manage chronic pain, is safe for participants. An initial study reported no serious side effects among participants, indicating the program is generally well-received. Additionally, 90% of participants expressed satisfaction with the program, demonstrating its acceptability. The program includes activities such as mindfulness and pain education, which are typically safe and gentle.12345

Why are researchers excited about this trial?

The RAMP Program for chronic pain is unique because it focuses on a comprehensive approach to managing pain rather than relying solely on medication. Unlike standard treatments such as opioids, NSAIDs, or physical therapy, RAMP integrates physical, psychological, and lifestyle changes to address the root causes of chronic pain. Researchers are excited because this method could provide more sustainable pain relief and improve overall quality of life without the side effects associated with long-term medication use. By empowering patients with self-management techniques, the RAMP Program has the potential to revolutionize how chronic pain is treated.

What evidence suggests that the RAMP Program is effective for managing chronic pain?

Research has shown that the RAMP mind-body program, which participants in this trial may receive, can help manage chronic pain, especially for rural Veterans. In past studies, 90% of participants reported satisfaction with the program. Early results indicate that the program is practical and well-received. It includes pain education, mindfulness, specific exercises, and strategies to change thoughts about pain. These tools aim to gradually reduce the impact of pain on daily life.12367

Who Is on the Research Team?

RE

Roni Evans, DC, PhD, MS

Principal Investigator

University of Minnesota

KH

Katherine Hadlandsmyth, PhD

Principal Investigator

University of Iowa

DB

Diana Burgess, PhD

Principal Investigator

Minneapolis Veterans Affairs Medical Center

Are You a Good Fit for This Trial?

This trial is for adults (18+) living in rural areas who are Veterans with chronic pain, have had at least two pain diagnoses over the past two years, experience pain most days, and can join online sessions using an internet-connected device.

Inclusion Criteria

I am an adult living in a rural area with chronic pain and internet access.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the RAMP mind-body program via group telehealth, focusing on pain education, mindfulness, pain-specific exercises, and cognitive behavioral strategies

6 months
Telehealth sessions at baseline, 3 months, and 6 months

Follow-up

Participants are monitored for safety and effectiveness after treatment, with assessments of pain interference, intensity, and other health measures

6 months
Assessments at baseline, 3 months, and 6 months

What Are the Treatments Tested in This Trial?

Interventions

  • RAMP Program

Trial Overview

The study tests the RAMP mind-body program delivered via telehealth. It teaches Veterans skills to manage chronic pain by focusing on the connection between body and mind through remote group sessions.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention
Group II: Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Minneapolis Veterans Affairs Medical Center

Lead Sponsor

Trials
77
Recruited
355,000+

Citations

Reaching Rural Veterans: Applying Mind-Body Skills for Pain ...

RAMP-WH is a 12-week program, comprised of pain education, mindfulness, pain specific exercises, and cognitive behavioral strategies.

A mind-body program for rural Veterans with pain (RAMP)

The primary effectiveness outcome is pain interference at 3 and 6 months. Secondary outcomes include opioid use and the NIH HEAL ...

Reaching rural veterans: Applying mind-body skills for pain ...

The following milestones were met: 1) 40 rural VA patients with moderate to severe chronic pain were enrolled, 2) 90% of participants were satisfied with the ...

4.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/41629997/

Risk Assessment and Management Program (RAMP) on ...

Methods: The study is a 52-week, two-arm, parallel, open-label randomized clinical trial, evaluating the clinical efficacy of RAMP-Knee OA (N = ...

February 19, 2026: RAMP Pilot Study Supports Telehealth ...

“Pilot results demonstrated that RAMP is feasible and acceptable to rural Veterans with chronic pain,” the authors concluded. Because the ...

Reaching Rural Veterans: Applying Mind-Body Skills for Pain ...

... RAMP (pilot) ... greater likelihood of chronic pain and poorer outcomes. ... See the Data and Safety Management Plan (DSMP) Appendix A for additional details.

Risk Assessment and Management Program (RAMP) on knee ...

The study is a 52-week, two-arm, parallel, open-label randomized clinical trial, evaluating the clinical efficacy of RAMP-Knee OA (N = 114) versus usual care (N ...