MRI for Lung Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests new imaging techniques to track lung tumors during radiation treatment. By using a special type of MRI scan (Magnetic Resonance Imaging), researchers aim to better monitor the movement of the tumor and nearby organs during breathing. This information could lead to more precise radiation therapy for people with lung cancer. It suits adults diagnosed with certain stages of non-small cell lung cancer who can undergo MRI scans. As an unphased trial, this study allows patients to contribute to innovative research that could enhance future cancer treatments.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this MRI technique is safe for lung cancer patients?
Research has shown that MRI (magnetic resonance imaging) is generally safe. Many studies have successfully used MRI to detect lung cancer and other health issues. This imaging method does not use radiation, enhancing its safety profile.
Although MRI is non-invasive, some individuals might feel uncomfortable or anxious inside the machine. MRI has been used in hospitals for many years, and serious side effects are rare.
In summary, evidence suggests that MRI is well-tolerated and safe for most people. However, discussing any personal concerns or medical conditions with a healthcare provider before undergoing an MRI is important.12345Why are researchers excited about this trial?
Researchers are excited about using MRI for lung cancer because it offers a more detailed and dynamic view of tumors compared to standard CT scans. Unlike traditional imaging, MRI provides superior soft tissue contrast, which could lead to better tumor targeting during radiation therapy. This technique may improve the precision of treatment, potentially resulting in fewer side effects and better outcomes for patients.
What evidence suggests that this MRI technique is effective for lung cancer?
Research has shown that MRI, or magnetic resonance imaging, is a useful tool for checking lung cancer. In this trial, participants will receive a 4D MRI with surface monitoring as part of the research protocol. Studies have found that MRI effectively monitors the size and spread of tumors, which is crucial for planning treatment. It provides clear images without using radiation, making it safer for patients. MRI also aids doctors in understanding the extent of cancer spread, known as staging. Using MRI during radiation treatment can enhance accuracy by tracking the tumor in real-time, allowing for more precise targeting of the cancer.12678
Who Is on the Research Team?
Amit Sawant, PhD
Principal Investigator
University of Maryland, Baltimore
Are You a Good Fit for This Trial?
This trial is for individuals with non-small cell lung cancer who are scheduled to undergo radiation therapy. Participants must be able to have an MRI scan and tolerate lying still for imaging before and during their treatment.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging
Participants receive a 4D CT Simulation and a 4D MRI with surface monitoring at baseline
Radiation Treatment
Participants undergo radiation treatment with additional fluoroscopy imaging and surface monitoring
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MRI
Trial Overview
The study is testing the use of four-dimensional MRI scans and x-ray fluoroscopy images to track lung tumors and nearby organs in real time as patients breathe during radiation treatments.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
At baseline, patients will receive a 4D CT Simulation (standard of care) along with a 4D MRI with surface monitoring (research). During their radiation treatment, they will receive additional fluoroscopy imaging and surface monitoring.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Maryland, Baltimore
Lead Sponsor
Citations
Magnetic resonance imaging for lung cancer screen - PMC - NIH
It has been suggested that dynamic CE MRI is effective for assessment of tumor angiogenesis (27). The lack of ionizing radiation makes MRI a safe tool for ...
Contribution of magnetic resonance imaging in lung cancer ...
In this review, we describe the contribution of MRI in lung cancer staging focusing on solid pulmonary nodule characterization and TNM staging assessment.
Magnetic resonance imaging for lung cancer: a state-of-the ...
Thus, several studies show that lung MRI could be a potentially effective screening tool, with a performance comparable to that of LDCT, but ...
A review of the role of MRI in diagnosis and treatment ... - PMC
MRI-guidance can improve radiotherapy in lung cancer despite physical challenges. •. Real-time tracking and better soft tissue contrast also facilitate adaptive ...
State of the Art MR Imaging for Lung Cancer TNM Stage ...
These studies reported a diagnostic accuracy of whole-body MRI ranging from 66% to 98.6% of PET/MRI with and without signal intensity ranging from 57.1% to 98.6 ...
The impact of brain MRI screening on stage IV NSCLC ...
Our study supports the use of brain MRI screening among good PS patients diagnosed with stage IV NSCLC lung cancer.
Rates of Overall Survival and Intracranial Control in the ...
These findings suggest that patients with LS-SCLC staged with MRI who undergo PCI after thoracic radiation treatment were not associated with a decreased risk ...
Magnetic resonance imaging for staging of non-small-cell lung ...
DW-MRI is a meanwhile widely established MRI technique that is able to detect and identify hyper-cellular tissues such as metastases from cancer due to their ...
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