Physical Activity Intervention for Breast Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how different exercise plans might help breast cancer survivors become more active. The study aims to determine if a "step-up" intervention, which includes extra support sessions, encourages those who aren't getting enough exercise to become more active and stay engaged. Researchers will divide participants into groups, following either an effort-based or an affect-based exercise prescription. Ideal candidates are breast cancer survivors who have not been very active recently and wish to increase their physical activity to improve their health. Participants need a smartphone and internet access to engage in study activities. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance exercise interventions for breast cancer survivors.
What prior data suggests that this physical activity intervention is safe for breast cancer survivors?
Research has shown that the exercise plans tested in this trial are generally safe for breast cancer survivors. Specifically, the Affect-based Exercise Prescription (Affect-Rx) was studied and found safe for those with stage II or higher breast cancer, with no harmful effects reported. This plan aims to boost mood during exercise, making it more enjoyable and easier to maintain.
Similarly, the Effort-based Exercise Prescription is also safe and beneficial. Studies indicate that this approach, which focuses on perceived exertion during exercise, helps manage cancer-related pain and improves quality of life. These findings suggest that the exercises are not only safe but also offer significant health benefits.
Overall, both types of exercise plans are well-tolerated and present no known safety risks, making them a good option for breast cancer survivors seeking to be more active.12345Why are researchers excited about this trial?
Researchers are excited about these exercise prescriptions for breast cancer survivors because they take a tailored approach to physical activity. Unlike standard exercise programs, the Affect-based Exercise Prescription focuses on how the activity makes participants feel, potentially improving adherence and enjoyment. Meanwhile, the Effort-based Exercise Prescription uses perceived exertion levels to customize workouts, which might help survivors manage fatigue and gradually increase their fitness. These innovative methods aim to enhance the physical and emotional well-being of breast cancer survivors, offering a more personalized and effective approach than traditional exercise programs.
What evidence suggests that this trial's treatments could be effective for breast cancer survivors?
This trial will compare different exercise prescriptions for breast cancer survivors. Studies have shown that exercise can greatly improve their health. Research indicates that regular physical activity enhances movement, increases muscle strength, and boosts overall physical ability. One study found that low to moderate intensity exercise three times a week reduced tiredness in survivors. Another study found that exercise plans tailored to personal needs, such as those based on individual effort or feelings, can improve quality of life. Additionally, exercise has been linked to better heart health and can even lower the risk of death in breast cancer survivors. Overall, these findings support the idea that exercise can significantly enhance life after breast cancer treatment. Participants in this trial will be assigned to different exercise prescriptions, such as Affect-based or Effort-based Exercise Prescriptions, to evaluate their effectiveness.678910
Are You a Good Fit for This Trial?
This trial is for breast cancer survivors who are interested in increasing their physical activity. Participants must be able to join remote exercise sessions and wear an activity monitor. Specific inclusion or exclusion criteria were not detailed.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo baseline assessment and are assigned to either Affect-based or Effort-based exercise prescription
Initial Intervention
Participants participate in three meetings with the interventionist to increase weekly exercise
Step-up Intervention
Participants performing <150 minutes of MVPA at 6 weeks are randomized to continue standard or step-up intervention
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Affect-based Exercise Prescription
- Effort-based Exercise Prescription
- Standard Exercise Promotion Program
- Step-up Exercise Promotion Program
Trial Overview
The study compares different ways of encouraging exercise: affect-based, effort-based, standard promotion, and a 'step-up' program for those less active at week 6. All programs are delivered remotely with support from an exercise specialist.
How Is the Trial Designed?
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Treatment groups
Experimental Treatment
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dartmouth-Hitchcock Medical Center
Lead Sponsor
Citations
Exercise effects on fatigue in breast cancer survivors after ...
Exercise at a low to moderate intensity, 20 min/day, three times per week, at 12-week follow-up reduced fatigue for breast cancer survivors who ...
NCT04903249 | A Single Arm Pilot Study to Refine a Novel ...
The purpose of this study is to refine the use of an affect-regulated exercise prescription for use with survivors of breast cancer.
Effect of supervised exercise on aerobic capacity in cancer ...
Survivors of cancer who participated in supervised aerobic exercise training improved aerobic capacity (VO2peak) more than controls
Effects of a Community-Based Multimodal Exercise Program ...
The main finding in this study is that outcome measures of health-related physical fitness and physical function (mobility, muscular strength, upper-extremity ...
(PDF) Effects of different exercise interventions on quality ...
We identified randomized controlled trials (RCTs) that evaluated how exercise interventions affect QoL in breast cancer survivors. Using ...
Exercise Promotion for Breast Cancer Survivors
Research shows that the exercise plans tested in this trial are generally safe for breast cancer survivors. Studies have not found any harmful effects from the ...
Exercise that feels as good as possible: Acceptability of an ...
An Affect-based exercise prescription (Affect-Rx) may be a viable strategy for supporting this effort. Aims. Guided by the ORBIT Model for ...
Which Exercise Prescriptions Improve Physical Fitness in ...
During active treatment, combined exercise significantly improved muscular strength, FEC, and cardiorespiratory fitness, but not fat-free mass.
Increasing physical activity among breast cancer survivors
... exercise to stage 0-III breast cancer survivors based on affect regulation. The novel intervention is called “Affect-Rx.” Primary Objective: To ...
A Randomized Two-Arm Proof of Concept Study Testing A Novel ...
The goal of this clinical trial is to test the effect of an affect-based exercise prescription on moderate-vigorous physical activity participation among ...
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