Modified Constraint Induced Movement Therapy for Cerebral Palsy

Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: University of Calgary
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore the costs of running a special day camp for children with hemiparesis (weakness on one side of the body) due to conditions like cerebral palsy or brain injury. The camp includes a week of modified constraint-induced movement therapy, where the stronger arm is restrained to encourage movement in the weaker arm, followed by a week of bimanual therapy, which involves using both hands together. It is designed for children with mild to moderate hemiparesis who can move their wrist and fingers, attend school full-time, and participate in group activities. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance therapeutic options for children with hemiparesis.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this therapy is safe for children with hemiparesis?

Research has shown that Modified Constraint Induced Movement Therapy (mCIMT) has been tested for safety and effectiveness in children with cerebral palsy. Studies have found that children generally tolerate this therapy well. For example, one study reported that participants experienced no major side effects. Another study indicated that mCIMT can improve movement skills without causing harm.

Some studies mention concerns about how results are reported, but these do not relate to safety. This therapy is also used for other conditions like stroke, with evidence supporting its safety. Overall, research suggests that mCIMT is safe for children with cerebral palsy, with no major safety issues identified.12345

Why are researchers excited about this trial?

Modified Constraint Induced Movement Therapy is unique because it combines two techniques: Constraint Induced Movement Therapy and Bimanual Therapy. Unlike traditional treatments for cerebral palsy, which often focus solely on improving movement in one hand or limb, this therapy encourages the use of both hands together, promoting more balanced motor skills. Researchers are excited about this approach because it aims to enhance overall functionality and independence in children with cerebral palsy, potentially offering more comprehensive benefits than current single-method therapies.

What evidence suggests that this therapy is effective for cerebral palsy?

Research has shown that modified constraint-induced movement therapy (mCIMT) can help children with cerebral palsy improve the use of their affected arm. One study found that this therapy significantly enhanced hand and motor skills. Another study demonstrated that children using mCIMT achieved better results than those receiving less intensive traditional therapies. This trial will evaluate mCIMT, which increases the natural use of the affected arm during activities requiring both hands. Additionally, longer therapy sessions may prove even more beneficial for children over five years old. Overall, mCIMT appears promising for improving arm function in children with weakness on one side of the body.12367

Are You a Good Fit for This Trial?

This trial is for children with hemiparesis due to conditions like brain injury, cerebral palsy, or alternating hemiplegia. Participants will attend a day camp focused on improving movement in limbs with reduced function.

Inclusion Criteria

I have mild to moderate weakness on one side of my body due to cerebral palsy or a brain injury.
I can move my wrist to a straight position and bend and straighten my fingers.
Written consent
See 2 more

Exclusion Criteria

I struggle to focus for 1 to 1.5 hours.
I have severe weakness on one side of my body due to brain injury or cerebral palsy.
I cannot move my wrist on the side affected by paralysis.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Constraint Induced Movement Therapy

Participants complete a day camp with constraint induced movement therapy

1 week
Daily visits (in-person, 9am to 4pm)

Bimanual Therapy

Participants complete a day camp with bimanual therapy

1 week
Daily visits (in-person, 9am to 4pm)

Follow-up

Participants are monitored for safety and effectiveness after therapy

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Modified Constraint Induced Movement Therapy

Trial Overview

The study tests a full-day modified constraint induced movement therapy camp. Week 1 involves therapy to improve use of the weaker limb, and Week 2 focuses on using both limbs together (bimanual therapy).

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Modified Constraint Induced Movement TherapyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials
827
Recruited
902,000+

Citations

The effectiveness of modified constraint-induced movement ...

Based on the current evidence, m-CIMT may improve upper limb function in children with CP, but due to the very low certainty of evidence and ...

Effectiveness of Modified Constraint-Induced Movement ...

RESULTS. Both groups demonstrated a significantly large and equal improvement in hand and gross motor function posttreatment (p < .001) and high treatment ...

Is more always better? Effectiveness of constraint‐induced ...

Applying a CIMT protocol with a dosage between 30 and 60 h seems to improve the spontaneous use of the affected upper limb during bimanual tasks ...

Motor learning curve and long-term effectiveness of ...

The findings suggest that children of 5 years and older might profit from a longer period of mCIMT than 54 h to reach their maximum unimanual capacity.

Constraint-Induced Movement Therapy for Cerebral Palsy

All CIMT groups improved significantly more in parent-reported functioning, compared with that of UCT. Children with UCT also revealed objective ...

Pertinence of Constraint-Induced Movement Therapy in ... - PMC

CIMT has been found effective in restoring motor function in various conditions including stroke, cerebral palsy, traumatic brain injury (TBI), and more.

Evaluation of Effectiveness of Modified Pediatric Constraint ...

A series of pediatric Constraint-induced Movement Therapy (CIMT) sessions were conducted online on ten children with unilateral cerebral palsy ( ...