Functional Near Infrared Spectroscopy for Brain Injury
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new brain monitoring technique during heart surgery to identify brain injuries. The researchers aim to use a non-invasive tool called multichannel functional near-infrared spectroscopy (fNIRS), which checks oxygen levels in different brain areas simultaneously. This could help detect issues like strokes or memory problems that might occur after surgery. The trial suits adults scheduled for planned heart surgeries. Participants will wear a special cap during their surgery, and their care will remain unchanged. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could enhance surgical outcomes for future patients.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this brain monitoring technique is safe for use during cardiac surgery?
Research has shown that multichannel functional near-infrared spectroscopy (fNIRS) is a safe and non-invasive method for monitoring brain oxygen levels during surgery. Studies have found that fNIRS is easy to use and provides real-time information about oxygen in brain tissue, allowing it to detect potential brain injury without causing harm or discomfort.
The multichannel fNIRS device fits over the entire head, offering a comprehensive view of brain oxygen levels. This is particularly useful during surgeries, such as heart surgeries, where monitoring brain health is crucial. No reports of negative effects have emerged from using this type of brain monitoring. The device, worn like a cap during surgery, does not interfere with the procedure. Overall, current findings suggest that fNIRS is well-tolerated by patients and poses no safety concerns.12345Why are researchers excited about this trial?
Researchers are excited about using multichannel fNIRS monitoring during cardiac surgery because it offers a non-invasive way to monitor brain activity in real-time. Unlike traditional methods that might require more invasive approaches or provide less detailed information, fNIRS uses near-infrared light to track blood flow and oxygen levels in the brain. This technique could potentially lead to better outcomes by giving surgeons immediate feedback on brain function, helping to prevent complications during and after surgery.
What evidence suggests that multichannel fNIRS monitoring is effective for detecting brain injury in cardiac surgery?
Studies have shown that multichannel functional near-infrared spectroscopy (fNIRS), which participants in this trial will experience, effectively monitors brain oxygen levels during tasks. This non-invasive technique measures oxygen levels in different brain regions. Research indicates that it can cover the entire brain, which is crucial for identifying brain injuries that might occur during heart surgery. Multichannel fNIRS holds promise because it may detect changes that current methods miss, especially in high-risk areas. Initial findings suggest it can enhance patient care by offering more detailed brain monitoring during surgery.12346
Who Is on the Research Team?
Jason Chui, MD
Principal Investigator
Western University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgery and Monitoring
Participants undergo cardiac surgery while being monitored using multichannel fNIRS to assess cerebral oxygenation
Follow-up
Participants are monitored for safety and effectiveness after surgery
What Are the Treatments Tested in This Trial?
Interventions
- multichannel fNIRS monitoring
Find a Clinic Near You
Who Is Running the Clinical Trial?
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lead Sponsor
London Health Sciences Centre OR Lawson Research Institute of St. Joseph's
Lead Sponsor
London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
Lead Sponsor
Lawson Health Research Institute
Lead Sponsor