Mobile Brain and Balance Program for Concussion

HL
Overseen ByHyunhwa Lee, PhD, MSN, APRN, PMHNP-BC
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new program to aid athletes in recovering from sports-related concussions or mild head injuries. Participants will use a mobile app for 14 days, combining brain exercises, such as counting backwards, with light walking to improve thinking, balance, and mood recovery. This program, called BraW-Day™ (Brain & Walk Exercise Every Day), enhances recovery through daily activities. Participants will visit UNLV twice for assessments, perform daily 15-minute exercises at home, provide a saliva sample, and complete short questionnaires. Individuals who have experienced a sports-related concussion in the past 3-12 months, can walk lightly, and have a smartphone might be suitable candidates. Even without direct benefit, involvement can advance research for better recovery methods. As an unphased trial, participation can significantly contribute to pioneering research in concussion recovery.

Will I have to stop taking my current medications?

If you are currently on prescribed medications that may significantly affect cognitive function, balance, neurological function, or safe participation in light physical activity, you may not be eligible to participate in this trial.

What prior data suggests that this program is safe for concussion recovery?

Research has shown that exercises similar to those in the BraW-Day program are generally safe for individuals who have experienced a concussion. Studies indicate that combining physical activities, like walking, with simple cognitive tasks, such as counting backwards, does not raise the risk of adverse effects. Light physical activity after a concussion is often recommended to aid recovery. This approach is typically well-tolerated, allowing most people to participate without issues. While no treatment is entirely risk-free, current evidence suggests that the BraW-Day program is a safe option for those recovering from a concussion.12345

Why are researchers excited about this trial?

Researchers are excited about the BraW-Day™ program for concussion recovery because it offers a unique, home-based approach that combines physical and cognitive exercises. Unlike standard treatments, which often focus on rest and gradual return to activities, BraW-Day™ encourages daily 15-minute sessions of walking paired with cognitive tasks, like counting backwards or performing memory exercises. The program's adaptability, with increased cognitive task difficulty and optional guided breathing exercises, makes it stand out. This mobile intervention leverages technology via the Uplode app, making it an accessible and engaging option for patients recovering from concussions.

What evidence suggests that the BraW-Day™ program is effective for concussion recovery?

Research has shown that exercise can help people recover faster from concussions. One study found that those who exercised recovered about 4.6 days sooner than those who did not. Aerobic exercise, which increases heart rate, can boost brain function and ease concussion symptoms. Some research suggests that combining physical and mental exercises can further speed up recovery. In this trial, participants will engage in the BraW-Day™ program, which includes walking and brain exercises, and it may aid recovery from sports-related concussions.13456

Are You a Good Fit for This Trial?

This trial is for people ages 18-40 who had a sports-related concussion or mild head injury in the past 3-12 months. Participants need to have a smartphone and be able to safely do light walking and simple brain tasks at home.

Inclusion Criteria

I had a sports-related concussion or mild brain injury 3-12 months ago.
Able to provide informed consent
Meets criteria for mTBI based on a standardized screening method (e.g., Ohio State University TBI Identification Method)
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Exclusion Criteria

Inability to read or understand English as study materials and the mobile application are currently available only in English
I am unable to use a smartphone or mobile device needed for the study.
History of moderate or severe traumatic brain injury
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (in-person)

Baseline Assessment

Initial assessments including cognitive function, physiological markers, and symptom severity

1 day
1 visit (in-person)

Treatment

Participants engage in a 14-day home-based dual-task intervention using the BraW-Day™ app

14 days
Daily home-based sessions

Post-Intervention Assessment

Follow-up assessments to evaluate changes in cognitive function, symptom severity, and physiological markers

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • BraW-Day™ (Brain & Walk Exercise Every Day)

Trial Overview

The study tests BraW-Day™, a home-based program using a mobile app that combines daily brain exercises (like counting backwards) with walking, over 14 days. Progress is measured through two in-person visits, saliva samples, and questionnaires.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: 14-Day BraW-Day™ InterventionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Hyunhwa Lee

Lead Sponsor

University of Nevada, Las Vegas

Collaborator

Trials
81
Recruited
14,700+

Citations

Exercise is Medicine for Concussion - PMC - NIH

This article reviews recent observational and experimental data and presents the evidence that sub-threshold aerobic exercise normalizes the cerebrovascular ...

Mobile Dual-Task Brain and Balance Intervention for ...

This 14-day program uses a mobile app on your smartphone and combines simple brain exercises (like counting backwards) with walking exercises.

Rest and exercise early after sport-related concussion

In a meta-analysis of seven studies, PA and prescribed exercise improved recovery by a mean of −4.64 days (95% CI −6.69, –2.59). After SRC, ...

Exercise After a Concussion: What to Do if You Feel Worse

Most doctors advised patients with a concussion to rest completely in a dark room from mental and physical activities until concussion symptoms disappeared.

Dual-Task Exercise for Concussions · Info for Participants

Some studies found that those who followed a prescribed exercise routine recovered about 4.6 days faster than those who didn't exercise. Starting regular ...

When Is It Safe to Work Out Following a Concussion?

Key takeaways: Experts agree that light physical activity after a concussion improves recovery time. Begin with light exercise, like short walks ...