Near-infrared Light Therapy for Brain Aging

This trial explores whether near-infrared light therapy on the brain can improve blood flow and cognitive skills in older adults. Researchers are testing if this therapy, known as Transcranial Photobiomodulation, boosts brain activity during tasks like memory games and finger tapping, and reduces brain inflammation and stress. Participants will receive either the actual light therapy or a placebo, allowing for comparisons between the two. The trial invites individuals who can speak and read English, have good hearing and vision, and do not have active brain diseases or uncontrolled health conditions. As an unphased study, this trial offers participants the chance to contribute to innovative research that could enhance cognitive health in older adults.

The trial does not specify if you need to stop taking your current medications, but it excludes those with certain medical conditions or those taking specific dietary supplements. It's best to discuss your medications with the trial team to see if they affect your eligibility.

Previous studies have shown that transcranial photobiomodulation (tPBM) is safe and well-tolerated. Research indicates it is a non-invasive method that can enhance brain and blood vessel health. Many studies report improvements in thinking and memory, even in individuals with conditions like dementia and brain injuries.

Researchers are excited about transcranial photobiomodulation for brain aging because it offers a non-invasive approach using near-infrared light to potentially enhance brain health. Unlike current treatments that often rely on medication, this therapy uses light to stimulate brain activity and improve cognitive function. Its unique delivery method, through a device like the Vielight Neuro Rx Gamma, allows for targeted therapy with minimal side effects, setting it apart from traditional pharmacological options.

Research has shown that transcranial photobiomodulation (tPBM) can improve thinking and memory by affecting brain activity. Studies found that 82.9% of participants experienced better cognitive function after receiving tPBM. This trial will compare two groups: one receiving active near-infrared light therapy and another receiving sham therapy. The active treatment uses near-infrared light, which may improve brain cell health and increase blood flow in the brain. Early data suggest that tPBM can benefit individuals with early Alzheimer's and mild memory problems. Overall, initial findings support its potential to enhance memory and mental clarity.¹²³⁴⁵