Biocidin for Biofilms

CD
Overseen ByChris D'Adamo, Ph.D.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate how a botanical formula called Biocidin liquid affects oral biofilms, which are layers of bacteria that can form in the mouth. Participants will use Biocidin for two weeks to determine its effectiveness in managing these biofilms. The trial is open to adults aged 25 and older who can commit to maintaining their current oral health routines and diet during the study. As an unphased trial, it offers a unique opportunity to contribute to the scientific understanding of natural treatments for oral health.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. However, you must not change your oral health practices or dietary habits during the study.

What prior data suggests that Biocidin Liquid is safe for use in healthy adults?

Research shows that Biocidin Liquid is generally safe when used as directed. Studies have found that even in higher amounts, Biocidin can effectively combat harmful bacterial layers, though this might not reflect typical daily use. The product is popular and has undergone lab testing for its wide-ranging benefits, including supporting gut health and eliminating harmful bacteria. Additionally, safety information for one of Biocidin's ingredients indicates it is safe even in much larger amounts than usually taken. Overall, available research considers Biocidin safe for use.12345

Why are researchers excited about this trial?

Unlike standard treatments for biofilms, which often include antibiotics or mechanical removal, Biocidin Liquid is a broad-spectrum botanical formula. Researchers are excited about this treatment because it leverages natural plant compounds to disrupt biofilms, which are protective layers that bacteria form to shield themselves. This new approach can potentially enhance treatment effectiveness by breaking down these barriers, making bacteria more vulnerable to eradication without relying solely on traditional antibiotics.

What evidence suggests that Biocidin Liquid is effective for oral biofilms?

Research has shown that Biocidin Liquid, the treatment under study in this trial, can significantly reduce biofilms, which are groups of bacteria that adhere to surfaces. One study found that a single dose of Biocidin reduced both these adherent bacteria and those floating freely by more than 100 times. Another study demonstrated that Biocidin is highly effective against these bacteria when used in higher amounts. These findings suggest that Biocidin could be a strong option for combating biofilms, especially in the mouth.23678

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 25 or older who speak English. Participants must be willing to take Biocidin as directed and not change their diet or oral health habits for two weeks. They also need to agree to do an oral microbiome test before and after using Biocidin.

Inclusion Criteria

I can read and speak English.
I am willing to take Biocidin orally as directed for two weeks.
I am 25 years old or older.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive Biocidin liquid for 2 weeks to evaluate its effects on oral biofilms

2 weeks
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

2-4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Biocidin Liquid

Trial Overview

The study is testing the effects of a liquid called Biocidin on oral biofilms in a single-arm, open-label trial. Participants will use the recommended dose of Biocidin for two weeks, with results assessed by SimplyPERIO tests.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Biocidin LiquidExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

OvationLab

Lead Sponsor

Trials
1
Recruited
150+

Citations

Activity of Biocidin® against microbial biofilms - PMC - NIH

Overall, we found a significant decrease (>2 log) in biofilm and planktonic populations upon exposure to a bolus dose of Biocidin®, while a 24- ...

NCT07408245 | Effects of Biocidin on Oral Biofilms

A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of ...

Preliminary Report on Activity of Biocidin against Multiple ...

Overall, Biocidin seems to be extremely effective against planktonic microbial populations at concentrations of 25% or above.

4.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/41684696/

Activity of Biocidin® against microbial biofilms

A single (bolus) dose of Biocidin® resulted in a significant decrease (> 2 Log) of biofilm and planktonic populations, while a 24-h continuous ...

Biocidin for Biofilms · Info for Participants · Clinical Trial 2026

The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults.

Biocidin Botanicals FAQ

Safety data exists for tocophersolan at 300 times the amount consumed within our products. Our products do not contain peanuts. (Note: See FAQ specifically ...

Biocidin® Liquid - Broad-Spectrum Liquid Formula

This laboratory-tested, research-backed formula has far-reaching effects that include support for gut health, biofilm cleansing, immunomodulation, and

Preliminary Report on Activity of Biocidin against Multiple ...

Although 90% of cells in both planktonic (bul-liquid) and biofilm populations of all microorganisms tested are killed with 25% Biocidin ...