CRUSH Curriculum for Autism

(CRUSH Trial)

SF
Overseen BySusan Faja, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program called CRUSH (Competence in Romance and Understanding Sexual Health), designed to help autistic adults improve their skills in intimate relationships and learn more about sexual health. Researchers aim to determine if the program is practical, well-received, and shows signs of being helpful. Participants will engage in both group sessions and individual coaching. This trial suits autistic adults who speak English fluently and have not previously participated in similar sexual health or dating programs. As an unphased trial, it offers a unique opportunity for participants to contribute to innovative research that could enhance social and sexual well-being for autistic adults.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on behavioral intervention and does not mention medication changes.

What prior data suggests that the CRUSH curriculum is safe for autistic adults?

A previous study found the CRUSH program to be safe and well-received by participants. This program helps autistic adults learn about sexual education and relationship skills. Participants in earlier trials reported positive experiences, with no major safety concerns. The program includes group learning and one-on-one coaching, effectively improving skills without harm. Since the trial focuses on education and coaching, physical side effects are not an issue. Overall, the CRUSH program appears to be a safe choice for those seeking to improve their relationship skills.12345

Why are researchers excited about this trial?

Researchers are excited about the CRUSH Curriculum because it offers a new approach to helping individuals with autism navigate romance and sexual health. Unlike standard educational programs, which might not specifically address the unique challenges faced by people with autism in these areas, the CRUSH Curriculum is tailored to build competence and understanding in romantic contexts. This targeted intervention aims to empower participants by enhancing their social skills and self-awareness, potentially leading to more fulfilling personal relationships.

What evidence suggests that the CRUSH curriculum is effective for autistic adults?

Research shows that the CRUSH program helps autistic adults learn about sexual education and relationship skills. Early results suggest that this program can increase knowledge about dating and sexual health. In this trial, participants will receive the CRUSH Curriculum, which includes both group sessions and one-on-one coaching. Past studies have demonstrated that this combination effectively helps participants gain a better understanding and improved skills for intimate relationships. This approach has shown promise in meeting the unique needs of autistic adults in these areas.12345

Are You a Good Fit for This Trial?

This trial is for adults with Autism Spectrum Disorder who are interested in improving their intimate relationship skills. They should be able to communicate and participate in a group setting, as well as provide feedback after sessions.

Inclusion Criteria

Fluent in English
I am between 18 and 30 years old.
Ability to provide consent for the protocol and understand task demands. The Wechsler Abbreviated Scale of Intelligence, Second Edition (WASI-2) may be used to confirm cognitive level. In prior work, adults with a full-scale IQ of 70 or above on the WASI-2 typically meet this criterion, but a licensed clinician will review individuals who fall below an IQ of 70 on an individual basis to determine eligibility
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Exclusion Criteria

Major mental illness (e.g., bipolar disorder, schizophrenia, or psychosis)
I primarily speak a language other than English.
My ASD is due to a known genetic reason like Fragile X.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (virtual)

Baseline Assessment

Participants complete baseline assessments of knowledge and behaviors related to dating and sexual health

1 week
1 visit (in-person)

Treatment

Participants undergo 20 sessions of the CRUSH curriculum plus 1-1 coaching sessions

20 weeks
20 sessions (in-person)

Midpoint Assessment

Participants are assessed midway through the intervention to evaluate progress

1 week
1 visit (in-person)

Post-intervention Assessment

Participants complete post-intervention assessments to evaluate the effectiveness of the CRUSH curriculum

1 week
1 visit (in-person)

Follow-up

Participants are monitored for long-term effects and retention of knowledge and skills

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Competence in Romance and Understanding Sexual Health (CRUSH)

Trial Overview

The CRUSH curriculum, which includes group-based behavioral intervention and one-on-one coaching aimed at sexual education and enhancing relationship skills for autistic adults, is being tested against a waitlist control.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: CRUSH InterventionExperimental Treatment1 Intervention
Group II: WaitlistActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Boston Children's Hospital

Lead Sponsor

Trials
801
Recruited
5,584,000+

Citations

Piloting the Competence in Romance and Understanding ...

CRUSH is a group-based behavioral intervention plus 1-1 coaching designed to provide sexual education and improve the skills of autistic adults ...

A Pilot Investigation of the Competence In Romance ...

We aim to: (1) Evaluate the feasibility and acceptability of the CRUSH curriculum in the context of a clinical trial with a waitlist control condition. We ...

Study Details | NCT05910658 | First CRUSH: Piloting the ...

Provide documentation of a diagnosis of autism spectrum disorder. 3 visits to assess knowledge and behaviors related to dating and sexual health at each point ...

CRUSH: Developing a sexual education program for young ...

CRUSH, the Competence in Romance and Sexual Health program, aims to develop a sex education curriculum for young adults on the autism ...

First CRUSH: Piloting the Preliminary Feasibility and ...

Provide documentation of a diagnosis of autism spectrum disorder. 3 visits to assess knowledge and behaviors related to dating and sexual health ...