Intermittent Theta-Burst Stimulation for ADHD

(ACHIEVE Trial)

This trial explores a new treatment called Intermittent Theta Burst Stimulation (iTBS) to help manage ADHD symptoms, particularly impulsivity, in Veterans. iTBS is a non-drug method that uses magnetic fields to target and improve brain function. The trial includes two groups: one receiving real stimulation and another receiving sham (fake) stimulation for comparison. It suits Veterans diagnosed with ADHD who continue to experience symptoms despite stable treatment for at least six weeks. Participants should not have certain metal implants or devices like pacemakers that are unsafe for MRI scans. As an unphased trial, this study offers Veterans the chance to contribute to innovative research that could lead to new ADHD treatment options.

No, you don't have to stop taking your current medications. The trial requires that your medication regimen remains stable throughout the study.

Previous research has shown that intermittent theta burst stimulation (iTBS) is generally safe. In one study involving 165 children with ADHD, participants tolerated iTBS well, and no major side effects occurred. This treatment uses magnetic pulses to stimulate the brain. Despite its high-tech nature, it is non-invasive, requiring neither surgery nor medication. Most study participants report only mild discomfort, such as a tingling sensation on the scalp. These findings suggest that iTBS might be a safe option for those seeking non-drug treatments for ADHD.¹²³⁴⁵

Researchers are excited about Intermittent Theta-Burst Stimulation (iTBS) for ADHD because it offers a non-invasive approach that could provide quicker results compared to traditional treatments like medication and behavioral therapy. Unlike medications that alter brain chemistry, iTBS uses magnetic pulses to target specific brain areas, potentially reducing ADHD symptoms with fewer side effects. This method could revolutionize ADHD management by providing an effective alternative for individuals who may not respond well to conventional treatments.

Research has shown that Intermittent Theta Burst Stimulation (iTBS) might help treat ADHD. In one study, 75% of participants improved their ADHD symptoms after iTBS sessions twice a day for 10 days. Another study found similar results, with 75% of participants experiencing lasting benefits even after treatment ended. iTBS appears to support the brain's ability to control impulsive behavior. While more research is needed, these early findings suggest that iTBS could be a useful non-drug option for managing ADHD symptoms. Participants in this trial will receive either active iTBS or sham stimulation to further evaluate its effectiveness.¹²³⁴⁶