Healthy Home Interventions for Childhood Asthma
(INHALE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether simple home changes can help children with asthma breathe better. The focus is on reducing humidity and mold, known triggers of asthma symptoms. Families in the Cleveland area with a child diagnosed with asthma who own their homes may qualify to participate. One group will receive the healthy home intervention immediately, while the other will receive it after the study. The trial will compare asthma symptoms before and three months after these changes. As an unphased trial, it offers families a chance to directly improve their home environment and potentially enhance their child's health.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It seems focused on home interventions rather than medication changes.
What prior data suggests that these healthy home interventions are safe for children with asthma?
A previous study found that children in homes with healthy improvements experienced better asthma control and fewer emergency room visits. These improvements target moisture and mold reduction. Research has shown that homes with these changes see improvements in asthma symptoms without harmful effects. Another study found that similar improvements led to better asthma management and fewer hospital visits.
Overall, these changes appear safe and well-tolerated, aiming to improve living conditions to aid children's asthma. No reports of negative effects from these home-based changes have emerged, making them a promising way to manage asthma better.12345Why are researchers excited about this trial?
Researchers are excited about the Healthy Home Interventions for Childhood Asthma because it explores a novel approach to managing asthma by focusing on the home environment, specifically humidity levels. Unlike traditional treatments that primarily rely on medications like inhalers or corticosteroids to manage symptoms, this intervention aims to reduce asthma triggers at their source. By controlling humidity, the intervention could potentially lower the presence of common asthma triggers such as dust mites and mold. This approach not only targets the root cause but also offers a non-pharmacological option that could complement existing treatments and improve overall quality of life for children with asthma.
What evidence suggests that healthy home interventions are effective for reducing pediatric asthma?
Research has shown that making changes at home can greatly improve asthma in children. In this trial, some participants will receive a healthy home intervention that includes humidity control. Studies have found that such changes help control asthma better and reduce trips to the emergency room. For example, children in these programs were more than 2.5 times less likely to need emergency care. Families also noticed fewer asthma symptoms and gained more knowledge about managing the condition. Overall, this evidence suggests that simple home adjustments can significantly help manage children's asthma.36789
Who Is on the Research Team?
Bridget Hegarty, PhD
Principal Investigator
Case Western Reserve University
Are You a Good Fit for This Trial?
This trial is for children under 18 with a doctor-diagnosed asthma who live in Cleveland or nearby suburbs. A parent or guardian must be able to give consent, and if renting, the landlord must agree to home changes.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants in the treatment group receive low-cost humidity and mold reduction interventions in their homes
Follow-up
Participants are monitored for changes in asthma control and quality of life after the interventions
What Are the Treatments Tested in This Trial?
Interventions
- Healthy home intervention
Trial Overview
The study tests whether making low-cost changes at home to reduce humidity and mold can help improve asthma symptoms in children. Families are randomly assigned to get these interventions either during the study or after it ends.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Received the humidity interventions
No humidity interventions implemented
Find a Clinic Near You
Who Is Running the Clinical Trial?
Case Western Reserve University
Lead Sponsor
The Cleveland Clinic
Collaborator
Citations
Healthy Homes University: A Home-Based Environmental ...
Based on self-reported data collected from 243 caregivers at baseline and six months, the impact of asthma on these children was substantially reduced, and the ...
Home Visits for Children With Asthma Reduce Medicaid ...
Results showed significant improvements in asthma control, health care use, and environmental trigger reduction and a positive return on ...
The Impact of Asthma Health Education for Parents of ...
The purpose of this study was to test the effectiveness of an educational intervention based on the asthma and healthy homes curriculum targeting parents of ...
4.
publications.aap.org
publications.aap.org/pediatrics/article/151/5/e2022058351/191045/A-Health-System-Initiated-Intervention-toA Health System-Initiated Intervention to Remediate ...
CAPP+ participants reported quality of life improvements extending beyond their child's physical health. Several noted that the aesthetic ...
Evidence-based pediatric asthma interventions and ...
Results: Home-based asthma education and environmental interventions have proven to be effective. The programs reviewed varied in types of interventions, ...
Healthy Homes: In-Home Environmental Asthma Intervention ...
Objectives. We evaluated health outcomes associated with in-home interventions in low-income urban households with children with asthma. Methods.
An Evaluation of a State-Funded Healthy Homes ...
Main outcome measure(s): The analysis compares improvements across the 3 groups for measures of asthma self-management, health care access, morbidity, and ...
8.
nchh.org
nchh.org/resource-library/case-studies_the-benefits-of-home-visits-for-children-with-asthma.pdfThe Benefits of Home Visits for Children with Asthma
Multnomah County Healthy Homes' participants were over 2½ times less likely to use the emergency department after the intervention. Savings of approximately ...
Effect of indoor environmental interventions in the home on ...
We present a systematic review of the effect of in-home environmental interventions on clinically relevant asthma outcomes in children. Evidence regarding “Home ...
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