80 Participants NeededMy employer runs this trial

Healthy Home Interventions for Childhood Asthma

(INHALE Trial)

Recruiting at 1 trial location
BH
Overseen ByBridget Hegarty, PhD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Case Western Reserve University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether simple home changes can help children with asthma breathe better. The focus is on reducing humidity and mold, known triggers of asthma symptoms. Families in the Cleveland area with a child diagnosed with asthma who own their homes may qualify to participate. One group will receive the healthy home intervention immediately, while the other will receive it after the study. The trial will compare asthma symptoms before and three months after these changes. As an unphased trial, it offers families a chance to directly improve their home environment and potentially enhance their child's health.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on home interventions rather than medication changes.

What prior data suggests that these healthy home interventions are safe for children with asthma?

A previous study found that children in homes with healthy improvements experienced better asthma control and fewer emergency room visits. These improvements target moisture and mold reduction. Research has shown that homes with these changes see improvements in asthma symptoms without harmful effects. Another study found that similar improvements led to better asthma management and fewer hospital visits.

Overall, these changes appear safe and well-tolerated, aiming to improve living conditions to aid children's asthma. No reports of negative effects from these home-based changes have emerged, making them a promising way to manage asthma better.12345

Why are researchers excited about this trial?

Researchers are excited about the Healthy Home Interventions for Childhood Asthma because it explores a novel approach to managing asthma by focusing on the home environment, specifically humidity levels. Unlike traditional treatments that primarily rely on medications like inhalers or corticosteroids to manage symptoms, this intervention aims to reduce asthma triggers at their source. By controlling humidity, the intervention could potentially lower the presence of common asthma triggers such as dust mites and mold. This approach not only targets the root cause but also offers a non-pharmacological option that could complement existing treatments and improve overall quality of life for children with asthma.

What evidence suggests that healthy home interventions are effective for reducing pediatric asthma?

Research has shown that making changes at home can greatly improve asthma in children. In this trial, some participants will receive a healthy home intervention that includes humidity control. Studies have found that such changes help control asthma better and reduce trips to the emergency room. For example, children in these programs were more than 2.5 times less likely to need emergency care. Families also noticed fewer asthma symptoms and gained more knowledge about managing the condition. Overall, this evidence suggests that simple home adjustments can significantly help manage children's asthma.36789

Who Is on the Research Team?

BH

Bridget Hegarty, PhD

Principal Investigator

Case Western Reserve University

Are You a Good Fit for This Trial?

This trial is for children under 18 with a doctor-diagnosed asthma who live in Cleveland or nearby suburbs. A parent or guardian must be able to give consent, and if renting, the landlord must agree to home changes.

Inclusion Criteria

My child under 18 has been diagnosed with asthma.
Parent/guardian able to complete informed consent
Residence within the City of Cleveland or immediate suburbs (e.g., East Cleveland, Garfield Heights, Warrensville Heights, Parma, Brook Park, Brooklyn/Old Brooklyn)

Exclusion Criteria

Rental property with landlord unwilling or unable to give consent for remediation
I am over 18 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants in the treatment group receive low-cost humidity and mold reduction interventions in their homes

3 months
Home visits for intervention implementation

Follow-up

Participants are monitored for changes in asthma control and quality of life after the interventions

3 months
Follow-up assessments at 3 months

What Are the Treatments Tested in This Trial?

Interventions

  • Healthy home intervention

Trial Overview

The study tests whether making low-cost changes at home to reduce humidity and mold can help improve asthma symptoms in children. Families are randomly assigned to get these interventions either during the study or after it ends.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention
Group II: ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Case Western Reserve University

Lead Sponsor

Trials
314
Recruited
236,000+

The Cleveland Clinic

Collaborator

Trials
1,072
Recruited
1,377,000+

Citations

Healthy Homes University: A Home-Based Environmental ...

Based on self-reported data collected from 243 caregivers at baseline and six months, the impact of asthma on these children was substantially reduced, and the ...

Home Visits for Children With Asthma Reduce Medicaid ...

Results showed significant improvements in asthma control, health care use, and environmental trigger reduction and a positive return on ...

The Impact of Asthma Health Education for Parents of ...

The purpose of this study was to test the effectiveness of an educational intervention based on the asthma and healthy homes curriculum targeting parents of ...

A Health System-Initiated Intervention to Remediate ...

CAPP+ participants reported quality of life improvements extending beyond their child's physical health. Several noted that the aesthetic ...

5.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/29722589/

Evidence-based pediatric asthma interventions and ...

Results: Home-based asthma education and environmental interventions have proven to be effective. The programs reviewed varied in types of interventions, ...

Healthy Homes: In-Home Environmental Asthma Intervention ...

Objectives. We evaluated health outcomes associated with in-home interventions in low-income urban households with children with asthma. Methods.

7.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/28121774/

An Evaluation of a State-Funded Healthy Homes ...

Main outcome measure(s): The analysis compares improvements across the 3 groups for measures of asthma self-management, health care access, morbidity, and ...

The Benefits of Home Visits for Children with Asthma

Multnomah County Healthy Homes' participants were over 2½ times less likely to use the emergency department after the intervention. Savings of approximately ...

Effect of indoor environmental interventions in the home on ...

We present a systematic review of the effect of in-home environmental interventions on clinically relevant asthma outcomes in children. Evidence regarding “Home ...