25 Participants NeededMy employer runs this trial

Music Therapy for Sickle Cell Disease

MB
Overseen ByManoj Bhasin, PhD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Emory University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether music therapy can reduce chronic pain and improve the overall well-being of young people with sickle cell disease. Participants will either listen to music through a special app daily for four weeks or engage with educational material. Researchers aim to determine if music therapy can lower pain levels, improve quality of life, and affect cells related to inflammation. This trial suits those diagnosed with sickle cell disease who experience chronic pain and have access to a smartphone or tablet. As an unphased trial, it offers a unique opportunity to explore innovative approaches to managing chronic pain and enhancing quality of life.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that music therapy is safe for youth with sickle cell disease?

Research has shown that music therapy is generally safe and easy to manage. In past studies involving individuals with sickle cell disease, music therapy improved mood, relaxation, and pain perception. Participants often reported feeling more relaxed and better able to manage their pain. These studies reported no major negative effects, suggesting that music therapy can safely help manage chronic pain and enhance the quality of life for those with sickle cell disease.12345

Why are researchers excited about this trial?

Researchers are excited about music therapy for sickle cell disease because it offers a non-invasive, drug-free approach to managing pain and stress, which are common issues for patients with this condition. Traditional treatments often rely on medications like opioids for pain management, which can have significant side effects and risk of dependency. Music therapy leverages the power of sound to promote relaxation and emotional well-being, potentially reducing the need for medication. Delivered through the Music Care© app, this therapy is accessible and can be personalized, allowing patients to engage in therapy sessions conveniently from their own homes. This innovative approach could transform how we support individuals with sickle cell disease, focusing on holistic wellness alongside conventional medical treatments.

What evidence suggests that music therapy might be an effective treatment for sickle cell disease?

Research has shown that music therapy can help manage pain and improve the quality of life for people with sickle cell disease. In this trial, participants in the Music Therapy group will engage in daily virtual music therapy sessions. Studies have found that active participation in music therapy helps patients handle sudden pain more effectively, similar to pain medication. People with sickle cell disease have also reported increased confidence in managing their condition and experiencing a better overall quality of life. Additionally, research across various medical fields supports the positive effects of music therapy. These studies provide promising evidence that music therapy could be a useful treatment option for those with sickle cell disease.12367

Who Is on the Research Team?

MB

Manoj Bhasin

Principal Investigator

Emory University

Are You a Good Fit for This Trial?

This trial is for young people diagnosed with sickle cell disease who have had ongoing or repeated pain for at least 3 months, experience emotional distress or trouble functioning because of it, can speak English, and have access to an internet-connected device.

Inclusion Criteria

My condition has lasted or come back for at least 3 months.
* Have access to a personal electronic device (e.g., phone, tablet) with access to the internet
* English fluency (for survey completion)
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in 20-minute daily virtual music therapy sessions for 4 weeks using the Music Care© app

4 weeks
Daily virtual sessions

Follow-up

Participants are monitored for changes in pain characteristics, HRQoL, depressive symptoms, anxiety, and stress

1 week
1 visit (in-person or virtual)

What Are the Treatments Tested in This Trial?

Interventions

  • Music Therapy

Trial Overview

The study compares a 4-week music therapy program to standard care in youth with sickle cell disease. It looks at whether music therapy helps reduce pain and improve quality of life, as well as its effects on immune cells using advanced genetic testing.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Music Therapy groupExperimental Treatment1 Intervention
Group II: Control groupPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Emory University

Lead Sponsor

Trials
1,735
Recruited
2,605,000+

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

Citations

Effects of Music Therapy on Quality of Life in Adults with Sickle ...

Music therapy may assist adults with sickle cell disease in improving self-efficacy and quality of life. Introduction. Adults with sickle cell ...

Music Therapy Improves Ability to Cope with Pain for Patients ...

These studies support the benefits of music therapy for managing acute pain, improving self-efficacy, and improving sickle cell disease ...

Clinical Delivery and Effectiveness of Music Therapy in ... - PMC

Music therapy (MT) has been shown to improve outcomes for patients with sickle cell disease (SCD) and patients with hematologic and/or oncologic conditions ...

Study finds music therapy brings effective pain relief for ...

"Music almost works like pain medication when people are engaged in the experience." In this inherited anemia that renders the red blood cells ...

The effects of music therapy on transition outcomes in ...

Results: BEATS participants demonstrated a significant improvement in SCD knowledge (p = 0.0002) compared to baseline, an increase in acute care clinic, but not ...

Effects of Music Therapy on Quality of Life in Adults with ...

When comparing participants in music therapy versus participants in waitlist control, we found large effect sizes for self-efficacy (1.20), pain ...

Feasibility of Music Therapy in Sickle Cell Disease

In preliminary analyses, MT participants demonstrated significant mean improvements in self-efficacy (5.42), sleep disturbance (-1.49), pain ...