Neuromodulation for Parkinson's Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will compare different treatment schedules of combined transcranial direct current stimulation (tDCS) and transcranial ultrasound stimulation (TUS) in participants with Parkinson's disease. Participants will be randomly assigned to one of four groups: Standard (10 sessions delivered five times per week for two weeks), Distributed (six sessions delivered three times per week for two weeks), Short (five sessions delivered over one week), or Sham (10 sham sessions delivered five times per week for two weeks).
Are You a Good Fit for This Trial?
This trial is for people diagnosed with Parkinson's disease. Participants should not have any conditions that would make it unsafe to receive brain stimulation treatments.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- tDCS combined with TUS
Trial Overview
The study tests different schedules of two non-invasive brain stimulation techniques—tDCS and TUS—either alone or together, compared to a sham (placebo) treatment. Participants are randomly assigned to one of four groups.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Active Control
Placebo Group
tDCS combined with TUS for 10 sessions; 5/week for 2 weeks
tDCS and TUS for 5 sessions over 1 week
tDCS and TUS for 6 sessions; 3/week for 2 weeks
Sham stimulation for 10 sessions; 5/week for 2 weeks
Find a Clinic Near You
Who Is Running the Clinical Trial?
Felipe Fregni, MD, PhD, MPH
Lead Sponsor
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