Cardiac MRI for Right Atrial Clot in Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests the effectiveness of cardiac MRI scans (Cardiac Magnetic Resonance Imaging) in detecting and evaluating clots in the right atrium of the heart in cancer patients. Researchers aim to improve treatment decisions for those with clots linked to central venous catheters (special tubes used for cancer treatment). The trial seeks adult cancer patients who have had a central venous catheter for at least seven days and have no pre-existing heart conditions affecting blood flow. As an unphased trial, it provides a unique opportunity to contribute to research that could enhance future treatment options for cancer patients.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that cardiac magnetic resonance imaging (CMR) is safe for examining right atrial clots?
Research has shown that Cardiac Magnetic Resonance Imaging (CMR) is generally easy for patients to handle. This scan uses magnets and radio waves to create clear pictures of the heart. Unlike some other imaging methods, CMR does not use radiation, making it safer.
In past studies, patients did not report major side effects from CMR, indicating that the procedure is safe for most people, including those with cancer who may be at risk for blood clots in the heart.
Overall, CMR is non-invasive and poses minimal risk, making it a dependable choice for checking heart conditions.12345Why are researchers excited about this trial?
Cardiac Magnetic Resonance Imaging (CMR) is unique because it provides a non-invasive, detailed view of the heart, which can help in accurately diagnosing right atrial clots in cancer patients. Unlike traditional imaging methods such as CT scans or echocardiograms, CMR offers superior tissue characterization and clarity without exposure to radiation. Researchers are excited about this method because it might lead to earlier and more precise detection of clots, potentially improving outcomes for cancer patients with cardiac complications.
What evidence suggests that cardiac MRI is effective for examining right atrial clots in cancer?
Research has shown that cardiac magnetic resonance imaging (CMR), the investigational method used in this trial, effectively detects blood clots in the right atrium of the heart in cancer patients with central venous catheters. Studies have demonstrated that CMR excels at identifying blood clots inside the heart, aiding doctors in selecting better treatments. Specifically, one study found that CMR could successfully differentiate between heart clots and tumors, providing clear diagnostic results. CMR also produces detailed images without exposing patients to radiation, offering a significant advantage. Overall, CMR has shown promising results in accurately diagnosing heart-related clots in cancer patients.12356
Who Is on the Research Team?
Angel Chan, MD, PhD
Principal Investigator
Memorial Sloan Kettering Cancer Center
Are You a Good Fit for This Trial?
This trial is for people with any type or stage of cancer who have a central venous catheter and are suspected to have a clot or mass in the right atrium of the heart, as seen on initial cardiac MRI scans.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging Evaluation
Participants undergo cardiac magnetic resonance imaging (CMR) to evaluate the properties of central venous catheter-associated right atrial clot
Follow-up
Participants are monitored for changes in RA clot characteristics and therapeutic response using CMR
What Are the Treatments Tested in This Trial?
Interventions
- Cardiac Magnetic Resonance Imaging (CMR)
Trial Overview
The study is testing how well cardiac MRI can detect and characterize clots attached to catheters in the right atrium of the heart in cancer patients. The goal is to improve diagnosis and guide treatment decisions.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Memorial Sloan Kettering Cancer Center
Lead Sponsor
American Heart Association
Collaborator
Citations
A Study of Cardiac Magnetic Resonance Imaging (CMR) ...
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People with Cancer. Share. Print Email. Copy. Copied ...
Central venous catheter–related right atrial thrombus in ... - PMC
This case series highlights the indispensable role of CMR in identifying intracardiac thrombi among cancer patients, particularly following the detection of a ...
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ctv.veeva.com
ctv.veeva.com/study/a-study-of-cardiac-magnetic-resonance-imaging-cmr-for-evaluating-catheter-associated-right-atrialA Study of Cardiac Magnetic Resonance Imaging (CMR) for ...
The researchers are doing this study to see how well cardiac magnetic resonance imaging (CMR) scans can be used to examine the properties of ...
Cardiac MRI for Right Atrial Clot in Cancer
... Cardiac Magnetic Resonance Imaging (CMR) will have tolerable side effects & efficacy for patients with Cancer and Right atrial thrombus. See
Assessment of Cardiac Masses by Cardiac Magnetic ...
Among 53 cases that had histological correlation, 25 (47%) were benign, 26 (49%) were metastatic, and 2 (4%) were malignant primary cardiac ...
Huge Right Atrium Thrombosis Mimicking Myxoma
Right atrial thrombosis is a rare but serious condition that can mimic cardiac tumors like myxoma, posing diagnostic challenges.
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